Document Detail


Ring-closing metathesis: novel routes to aromatic heterocycles.
MedLine Citation:
PMID:  18381742     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Olefin metathesis has been established as an important and general reaction in synthetic organic chemistry. Recently, it has attracted interest as a powerful tool for the construction of aromatic heterocycles. The importance of heteroaromatic motifs in medicinal chemistry and biology, as well as the efficiency and wealth of metathesis transformations, have resulted in significant success in this rapidly developing area.
Authors:
Timothy J Donohoe; Lisa P Fishlock; Panayiotis A Procopiou
Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Chemistry (Weinheim an der Bergstrasse, Germany)     Volume:  14     ISSN:  0947-6539     ISO Abbreviation:  Chemistry     Publication Date:  2008  
Date Detail:
Created Date:  2008-06-26     Completed Date:  2008-09-26     Revised Date:  2009-08-04    
Medline Journal Info:
Nlm Unique ID:  9513783     Medline TA:  Chemistry     Country:  Germany    
Other Details:
Languages:  eng     Pagination:  5716-26     Citation Subset:  IM    
Affiliation:
Chemistry Research Laboratory, University of Oxford, Oxford, OX1 3TA UK. timothy.donohoe@chem.ox.ac.uk
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MeSH Terms
Descriptor/Qualifier:
Alkenes / chemistry*
Chemistry, Organic / methods*
Cyclization
Furans / chemical synthesis
Heterocyclic Compounds / chemical synthesis*
Hydrocarbons, Aromatic / chemical synthesis*
Indoles / chemical synthesis
Models, Chemical
Pyridines / chemical synthesis
Pyrroles / chemical synthesis
Stereoisomerism
Chemical
Reg. No./Substance:
0/Alkenes; 0/Furans; 0/Heterocyclic Compounds; 0/Hydrocarbons, Aromatic; 0/Indoles; 0/Pyridines; 0/Pyrroles

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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