Document Detail


Ring Enlargement versus Selenoetherification on the Reaction of Lactam-Tethered Allenols with Selenenylating Reagents.
MedLine Citation:
PMID:  22420734     Owner:  NLM     Status:  Publisher    
Abstract/OtherAbstract:
Lactam-tethered allenols, readily prepared from alpha-oxolactams, were used as starting materials for divergent reactivity with selenenylating reagents. Oxycyclization (spirocyclic selenolactams) or ring expansion (selenoquinolones) can be either achieved through both the choice of reagents and substrates. The biological activity of some of the synthesized heterocycles has additionally been evaluated in four human cancer cell lines.
Authors:
Benito Alcaide; Pedro Almendros; Amparo Luna; Gonzalo Gómez-Campillos; Maria Rosario Torres
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Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2012-3-15
Journal Detail:
Title:  The Journal of organic chemistry     Volume:  -     ISSN:  1520-6904     ISO Abbreviation:  -     Publication Date:  2012 Mar 
Date Detail:
Created Date:  2012-3-16     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  2985193R     Medline TA:  J Org Chem     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
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