Document Detail


Right ventricular involvement in Takotsubo cardiomyopathy.
MedLine Citation:
PMID:  17000628     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
AIMS: The aim of our study is to assess the incidence and clinical significance of right ventricular (RV) involvement in Takotsubo cardiomyopathy (TTC). METHODS AND RESULTS: Between February 2002 and December 2005, 47 patients with TTC underwent cardiovascular magnetic resonance (CMR) at our institutions. 13 patients with delayed initial CMR were excluded. In the remaining 34 patients (32 women), RV wall motion abnormalities (WMAs) were present in nine (26%). Left ventricular ejection fraction (LVEF) was significantly lower in patients with RV involvement (40 +/- 6 vs. 48 +/- 10%, P = 0.04). The most frequently affected RV segments were the apico-lateral (89%), the antero-lateral (67%), and the inferior segment (67%). All RV WMA improved or disappeared in eight of nine patients who underwent a follow-up CMR study. Pleural effusion was more common in patients with RV involvement (67 vs. 8%, P < 0.001) and was predictive of RV dysfunction (sensitivity 67% and specificity 92%). Significant or bilateral pleural effusions were seen exclusively in patients with RV involvement. CONCLUSION: RV involvement is common in TTC and seems to be associated with a more severe impairment in LV systolic function. It may be suspected by the presence of pleural effusion.
Authors:
Dariusch Haghi; Anastasios Athanasiadis; Theano Papavassiliu; Tim Suselbeck; Stephan Fluechter; Heiko Mahrholdt; Martin Borggrefe; Udo Sechtem
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Publication Detail:
Type:  Journal Article; Multicenter Study     Date:  2006-09-25
Journal Detail:
Title:  European heart journal     Volume:  27     ISSN:  0195-668X     ISO Abbreviation:  Eur. Heart J.     Publication Date:  2006 Oct 
Date Detail:
Created Date:  2006-10-04     Completed Date:  2007-03-29     Revised Date:  2007-11-28    
Medline Journal Info:
Nlm Unique ID:  8006263     Medline TA:  Eur Heart J     Country:  England    
Other Details:
Languages:  eng     Pagination:  2433-9     Citation Subset:  IM    
Affiliation:
Medical Department, University Hospital Mannheim, Theodor-Kutzer-Ufer 1-3, Mannheim 68167, Germany.
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MeSH Terms
Descriptor/Qualifier:
Aged
Aged, 80 and over
Cardiomyopathies / complications*
Coronary Angiography
Female
Heart Catheterization
Humans
Magnetic Resonance Angiography
Male
Prospective Studies
Retrospective Studies
Stroke Volume / physiology
Ventricular Dysfunction, Right / diagnosis,  etiology*
Comments/Corrections
Comment In:
Eur Heart J. 2007 Apr;28(8):1037-8; author reply 1038   [PMID:  17339266 ]

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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