Document Detail

Right ventricular function in patients with preserved and reduced ejection fraction heart failure.
MedLine Citation:
PMID:  19443468     Owner:  NLM     Status:  MEDLINE    
AIMS: To determine the prevalence of right ventricular (RV) dysfunction in patients with preserved left ventricular (LV) ejection fraction (EF) heart failure (HF) and to compare RV function between patients with preserved EF HF and those with reduced EF HF. METHODS AND RESULTS: Hundred patients (72 +/- 14 years, 59% male) with HF were prospectively enrolled. Fifty-one had preserved EF HF (LVEF > 50%). The prevalence of RV systolic dysfunction in patients with preserved EF HF was 33, 40, and 50%, by using RV fractional area change (FAC), tricuspid annular motion (TAM), and peak systolic tricuspid annular tissue velocity (S') criteria, respectively. Tricuspid S' and TAM correlated the best with LVEF (r = 0. 48, P < 0.01). Patients with preserved EF HF had higher RV FAC (54 +/- 18 vs. 36 +/- 20%, P < 0.01), TAM (17 +/- 1 vs.11 +/- 1 mm, P < 0.01), and tricuspid S' (14 +/- 6 vs. 9 +/- 4 cm/s, P < 0.01) compared with those with reduced EF HF. Of those 51 patients, 34% had tricuspid E/e' > 6 suggestive of elevated RV filling pressures. Early tricuspid inflow (E), early diastolic tricuspid annular tissue (e'), tricuspid E/e', and hepatic vein systolic velocities were also higher in patients with preserved EF HF. CONCLUSION: The prevalence of RV systolic and diastolic dysfunctions was not uncommon in patients with preserved EF HF. However, patients with preserved EF HF had milder degree of RV systolic and diastolic dysfunctions compared with those with reduced EF HF.
Sarinya Puwanant; Tiffany C Priester; Farouk Mookadam; Charles J Bruce; Margaret M Redfield; Krishnaswamy Chandrasekaran
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Publication Detail:
Type:  Journal Article     Date:  2009-05-13
Journal Detail:
Title:  European journal of echocardiography : the journal of the Working Group on Echocardiography of the European Society of Cardiology     Volume:  10     ISSN:  1532-2114     ISO Abbreviation:  Eur J Echocardiogr     Publication Date:  2009 Aug 
Date Detail:
Created Date:  2009-08-12     Completed Date:  2009-11-06     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  100890618     Medline TA:  Eur J Echocardiogr     Country:  England    
Other Details:
Languages:  eng     Pagination:  733-7     Citation Subset:  IM    
Division of Cardiovascular Diseases, Department of Internal Medicine, Mayo Clinic, Rochester, MN, USA.
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MeSH Terms
Chi-Square Distribution
Heart Failure / epidemiology,  physiopathology*,  ultrasonography*
Prospective Studies
Severity of Illness Index
Stroke Volume / physiology*
Ventricular Dysfunction, Right / epidemiology,  physiopathology*,  ultrasonography*

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