Document Detail

Right ventricular function in patients with reduced left ventricular function undergoing myocardial revascularization.
MedLine Citation:
PMID:  1543848     Owner:  NLM     Status:  MEDLINE    
Complex interrelationships exist between the right (RV) and the left ventricles (LV). Therefore, in 30 consecutive patients with reduced LV function (left ventricular ejection fraction [LVEF]) less than 40% undergoing myocardial revascularization, RV hemodynamics were studied from the beginning of anesthesia until the end of the operation. The data were compared with 30 consecutive patients with normal LVEF (greater than 70%). Ventricular function was assessed during left heart catheterization, which was carried out within 1 month of the operation. In addition to standard hemodynamic variables, RV ejection fraction (RVEF), RV end-diastolic volume (RVEDV), and RV end-systolic volume (RVESV) were monitored by the thermodilution technique. The two groups did not differ preoperatively with regard to RVEF, pressure (MAP, PAP, PCWP, RAP, RVPsyst, RVEDP), cardiac index (CI), and volume variables (RVESV, RVEDV). However, when the group with preoperatively reduced LVEF was subdivided into patients with severely reduced LVEF (less than 30%; n = 14; mean value 25.1%) and patients with moderately reduced LVEF (30%-40%; n = 16; mean value 37.3%), RVEF was significantly lower in the patients with a LVEF below 30% throughout the entire investigation period. RVEDV and RVESV were significantly higher in these patients. In conjunction with the lower RVEF and normal PAP, this suggests reduced RV function. It can be concluded that a severely reduced preoperative LVEF (less than 30%) may also be associated with impaired RV function.
J Boldt; B Zickmann; C Herold; F Dapper; G Hempelmann
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Journal of cardiothoracic and vascular anesthesia     Volume:  6     ISSN:  1053-0770     ISO Abbreviation:  J. Cardiothorac. Vasc. Anesth.     Publication Date:  1992 Feb 
Date Detail:
Created Date:  1992-04-16     Completed Date:  1992-04-16     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  9110208     Medline TA:  J Cardiothorac Vasc Anesth     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  24-8     Citation Subset:  IM    
Department of Anesthesiology and Intensive Care Medicine, Justus-Liebig-University Gissen, Germany.
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MeSH Terms
Analysis of Variance
Blood Pressure / physiology
Cardiac Output / physiology
Cardiac Volume / physiology
Cardiopulmonary Bypass
Epinephrine / therapeutic use
Heart Arrest, Induced
Heart Rate / physiology
Middle Aged
Myocardial Revascularization*
Vascular Resistance / physiology
Ventricular Function, Left / physiology*
Ventricular Function, Right / physiology*
Reg. No./Substance:

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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