| Right ventricular function in asymptomatic individuals with a systemic right ventricle. | |
| | |
MedLine Citation:
|
PMID: 16880099 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
BACKGROUND: In congenital heart defects where the morphologic right ventricle (RV) supports the systemic circulation, RV failure is common yet develops gradually. We hypothesized that patients who are asymptomatic may have unrecognized RV dysfunction. METHODS: Conventional and Doppler tissue/strain echocardiography were performed on consecutive patients with asymptomatic systemic RV caused by congenitally corrected transposition of the great arteries (ccTGA) and on age-matched control subjects. RV index of myocardial performance was measured using conventional echocardiography. Longitudinal tissue velocities, strain rate, and strain of the basal RV free wall were measured using Doppler tissue/strain echocardiography and compared with nonsystemic RV of the control subjects. RESULTS: Mean age was 39.5 +/- 14.6 (n = 13) and 36 +/- 24 (n = 10) years for ccTGA and control groups, respectively. Mean RV index of myocardial performance was higher in patients with ccTGA than in control subjects (0.66 +/- 0.25 vs 0.28 +/- 0.12, P < .001). Mean RV tissue displacement (10.8 +/- 4.5 vs 20.3 +/- 3.9 mm, P < .0001), peak systolic strain rate (-1.16 +/- 0.3 vs -2.23 +/- 0.9 s(-1), P = .005), and peak systolic strain (-17.3 +/- 8.0 vs -30.6 +/- 11.0%, P = .008) were significantly lower in patients with ccTGA compared with control subjects, respectively. CONCLUSION: Patients with asymptomatic ccTGA have quantifiable RV dysfunction by echocardiography. |
| | |
Authors:
|
J Martijn Bos; Donald J Hagler; Suchaya Silvilairat; Allison Cabalka; Patrick O'Leary; Otto Daniels; Fletcher A Miller; Theodore P Abraham |
Related Documents
:
|
11773929 - Influence of left ventricular size and hemodynamics on the systolic longitudinal myocar... 17848839 - Early abnormalities of left ventricular myocardial characteristics associated with subc... 3335699 - Sensitivity of isovolumic relaxation to hypothermia during myocardial infarction. 19163439 - Assessment of myocardial deformations from untagged cardiac cine mri. 6501719 - Diagnosis of constrictive pericarditis by two-dimensional echocardiography: studies in ... 3916529 - Left ventricular function of heart allografts during acute rejection: an echocardiograp... 2018239 - Epa in the prevention of restenosis post ptca. 9170829 - Thrombolytic therapy for mitral valve thrombosis. 18307449 - Live/real time three-dimensional transthoracic echocardiographic findings in primary le... |
Publication Detail:
|
Type: Controlled Clinical Trial; Journal Article |
Journal Detail:
|
Title: Journal of the American Society of Echocardiography : official publication of the American Society of Echocardiography Volume: 19 ISSN: 1097-6795 ISO Abbreviation: J Am Soc Echocardiogr Publication Date: 2006 Aug |
Date Detail:
|
Created Date: 2006-08-01 Completed Date: 2006-09-18 Revised Date: 2007-11-02 |
Medline Journal Info:
|
Nlm Unique ID: 8801388 Medline TA: J Am Soc Echocardiogr Country: United States |
Other Details:
|
Languages: eng Pagination: 1033-7 Citation Subset: IM |
Affiliation:
|
Division of Cardiovascular Diseases, Mayo Clinic, Rochester, Minnesota, USA. |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Adult Echocardiography / methods* Female Heart Ventricles / ultrasonography* Humans Image Interpretation, Computer-Assisted / methods* Male Reproducibility of Results Risk Assessment / methods* Risk Factors Sensitivity and Specificity Transposition of Great Vessels / complications, surgery, ultrasonography* Ventricular Dysfunction, Right / etiology, ultrasonography* |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: What is the best approach for the assessment of left atrial size? Comparison of various unidimension...
Next Document: Pulmonary hemodynamic effects of dipyridamole infusion in patients with normal and elevated pulmonar...