Document Detail

Right ventricular function in ST elevation myocardial infarction: effect of reperfusion.
MedLine Citation:
PMID:  19640332     Owner:  NLM     Status:  MEDLINE    
PURPOSE: To investigate right ventricle function in successfully reperfused ST elevated myocardial infarction (STEMI) and to compare reperfusion strategies. METHODS: From January 2007 to August 2008, 33 patients with anterior myocardial infarction (MI) and 48 patients with non-anterior myocardial infarction were enrolled in this study. Patients were treated with thrombolytic therapy (TT) or primary percutanaeous coronary intervention (PPCI) (Primary intervention: 16 and 25 patients (anterior and non-anterior consecutively), thrombolytic therapy: 17 and 23 patients (anterior and non-anterior consecutively)). Right ventricle (RV) function was analyzed using tissue Doppler investigation (TDI) after 72 hr of successful reperfusion. RESULTS: There was no difference in right ventricle function assessed by right ventricle TDI Tei index between the PPCI and TT group (0.39+/-0.20 vs. 0.39+/-0,17). RV TDI Tei index increased in anterior MI patients treated with either PPCI or TT compared with control group (0.39+/-0.11 vs. 0.27+/-0.16, P=0.015 and 0.43+/-0.18 vs. 0.27+/-0.16 , P= 0.014 respectively). RV TDI Tei index did not differ between non-anterior MI patients treated with either PPCI or TT and control group (0.38+/-0.23 vs. 0.27+/-0.16, and 0.37+/-0.16 vs. 0.27+/-0.16, respectively). CONCLUSIONS: RV function deteriorated in STEMI compared with healthy controls. Contrary to the expectation, RV dysfunction was observed in anterior STEMI, but not in non anterior MI. There was no difference in RV function between the two treatment modalities.
Ozlem Karakurt; Ramazan Akdemir
Publication Detail:
Type:  Journal Article     Date:  2009-08-01
Journal Detail:
Title:  Clinical and investigative medicine. Médecine clinique et experimentale     Volume:  32     ISSN:  1488-2353     ISO Abbreviation:  Clin Invest Med     Publication Date:  2009  
Date Detail:
Created Date:  2009-07-30     Completed Date:  2009-10-08     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  7804071     Medline TA:  Clin Invest Med     Country:  Canada    
Other Details:
Languages:  eng     Pagination:  E285-92     Citation Subset:  IM    
Ministry of Health, Diskapi Yildirim Beyazit Research and Education Hospital, Department of Cardiology, Ankara, Turkey.
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MeSH Terms
Adrenergic beta-Antagonists / therapeutic use
Angioplasty, Transluminal, Percutaneous Coronary / methods
Heptanoic Acids / therapeutic use
Metoprolol / analogs & derivatives,  therapeutic use
Middle Aged
Myocardial Infarction / drug therapy,  physiopathology*,  therapy*
Myocardial Reperfusion*
Pyrroles / therapeutic use
Streptokinase / therapeutic use
Thrombolytic Therapy / methods
Ticlopidine / analogs & derivatives,  therapeutic use
Treatment Outcome
Ventricular Function, Right* / drug effects
Reg. No./Substance:
0/Adrenergic beta-Antagonists; 0/Heptanoic Acids; 0/Pyrroles; 0/metoprolol succinate; 110862-48-1/atorvastatin; 37350-58-6/Metoprolol; 55142-85-3/Ticlopidine; 90055-48-4/clopidogrel; EC 3.4.-/Streptokinase

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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