Document Detail

Right-ventricular failure following left ventricle assist device implantation.
MedLine Citation:
PMID:  23337895     Owner:  NLM     Status:  MEDLINE    
PURPOSE OF REVIEW: To review recent insights on right-ventricular failure (RVF) following left-ventricular assist device (LVAD) implantation.
RECENT FINDINGS: Even with the availability of new generation continuous mechanical assist devices, RVF after implantation of LVAD is still associated with high morbidity and mortality. Recent studies have tried to better define the risk of RVF using combined clinical scores and measures of right-ventricular function or strain. Small exploratory studies have also investigated the role of pulmonary vasodilators and phosphodiesterase inhibitors in selected patients receiving LVAD implantation.
SUMMARY: Measure of right-ventricular function could improve the risk stratification of RVF following LVAD implantation. Future multicenter studies are needed to validate right-ventricular risk scores and to develop evidence-guided preventive and therapeutic strategies.
Bhagat Patlolla; Ramin Beygui; Francois Haddad
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Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  Current opinion in cardiology     Volume:  28     ISSN:  1531-7080     ISO Abbreviation:  Curr. Opin. Cardiol.     Publication Date:  2013 Mar 
Date Detail:
Created Date:  2013-02-05     Completed Date:  2013-07-18     Revised Date:  2013-11-11    
Medline Journal Info:
Nlm Unique ID:  8608087     Medline TA:  Curr Opin Cardiol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  223-33     Citation Subset:  IM    
Department of Cardiothoracic Surgery, Stanford University, California, USA.
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MeSH Terms
Cardiopulmonary Bypass / adverse effects
Heart Failure / therapy*
Heart-Assist Devices / adverse effects*
Multiple Organ Failure / epidemiology,  physiopathology
Risk Factors
Ventricular Dysfunction, Right / classification,  etiology*,  physiopathology,  ultrasonography
Grant Support

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