Document Detail


Right ventricular endocardial thermography in transplanted and coronary artery disease patients: first human application.
MedLine Citation:
PMID:  20814045     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
BACKGROUND: We sought to evaluate for the first time in humans the safety and feasibility of right ventricular (RV) thermography in patients with coronary artery disease (CAD) and in patients after heart transplantation (Tx), in comparison to subjects without structural heart disease (controls).
METHODS: Ninety-one RV thermography procedures were performed in 16 patients with CAD, 19 hearttransplant recipients and 6 patients without structural heart disease. We recorded the temperature of the RV intracavitary blood and RV endocardial septum, and calculated their difference using a dedicated commercially available thermography catheter.
RESULTS: No complications were observed. CAD patients had a significantly higher temperature difference (0.19 +/- 0.11 degrees C) compared to both Tx patients (0.10 +/- 0.06 degrees C) and controls (0.07 +/- 0.04 degrees C) (p < 0.0001 and p = 0.003, respectively), whereas there was no significant difference between the Tx patients and controls (p = 0.65).
CONCLUSION: RV thermography in humans is feasible and safe. Patients with stable CAD present a significantly higher temperature difference in the RV endocardium compared to controls; clinically stable transplant recipients have temperatures similar to controls. This novel method corroborates previous findings supporting the inflammatory hypothesis of coronary atherosclerosis.
Authors:
Athanassios Manginas; Elias Andreanides; Epsilonvangelos Leontiadis; Petros Sfyrakis; Themistocles Maounis; Dimitrios Degiannis; Petros A Alivizatos; Dennis V Cokkinos
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Publication Detail:
Type:  Clinical Trial; Journal Article    
Journal Detail:
Title:  The Journal of invasive cardiology     Volume:  22     ISSN:  1557-2501     ISO Abbreviation:  J Invasive Cardiol     Publication Date:  2010 Sep 
Date Detail:
Created Date:  2010-09-03     Completed Date:  2011-01-19     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8917477     Medline TA:  J Invasive Cardiol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  400-4     Citation Subset:  IM    
Affiliation:
Department of Cardiology, Onassis Cardiac Surgery Center, 356 Syngrou Avenue, Kallithea, Athens, 176 74, Greece. esbarouni@yahoo.gr
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MeSH Terms
Descriptor/Qualifier:
Adult
Aged
Body Temperature*
Coronary Artery Disease / diagnosis*,  immunology
Endocardium
Feasibility Studies
Female
Heart Catheterization
Heart Septum
Heart Transplantation*
Heart Ventricles
Humans
Male
Middle Aged
Myocarditis / diagnosis
Thermography / instrumentation*,  methods*

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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