| Right ventricular ejection fraction during orthotopic liver transplantation: does anesthetic technique make a difference? | |
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MedLine Citation:
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PMID: 20381292 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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PURPOSE: The objective of this study is to evaluate the right ventricular ejection fraction (RVEF) during orthotopic liver transplantation (OLT) under 2 different anesthetic regimens: propofol vs isoflurane anesthesia. METHODS: We retrospectively analyzed the hemodynamic data of 25 (n = 25) patients who underwent OLT during the last year (2008). All patients were monitored with a modified pulmonary artery catheter, which continuously measured the RVEF. Anesthetic technique consisted of either isoflurane or total intravenous anesthesia with propofol. Surgical technique was similar between groups. RESULTS: Ten (n = 10) patients comprised the isoflurane group (I), whereas 15 (n = 15) patients received propofol anesthesia (P). The RVEF was not significantly different between groups (I vs P, baseline: 41% ± 9% vs 40% ± 6%; anhepatic phase: 36% ± 8% vs 35% ± 6%; postreperfusion: 41% ± 6% vs 41% ± 8%; P = not significant). CONCLUSIONS: The choice between propofol and isoflurane seems to have minimal influence on the RVEF during OLT, which followed similar trends regardless of the anesthetic technique. |
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Authors:
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Glauber Gouvêa; Rodrigo Diaz; Lúcio Auler; Renato Toledo; José Manoel Martinho |
Publication Detail:
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Type: Evaluation Studies; Journal Article Date: 2010-04-08 |
Journal Detail:
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Title: Journal of critical care Volume: 25 ISSN: 1557-8615 ISO Abbreviation: J Crit Care Publication Date: 2010 Dec |
Date Detail:
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Created Date: 2010-11-26 Completed Date: 2011-01-10 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 8610642 Medline TA: J Crit Care Country: United States |
Other Details:
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Languages: eng Pagination: 657.e1-6 Citation Subset: IM |
Copyright Information:
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Copyright © 2010 Elsevier Inc. All rights reserved. |
Affiliation:
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Liver Transplantation Unit, Department of Anesthesiology, Bonsucesso General Hospital, Rio de Janeiro 21041-030, Brazil. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Adult Aged Anesthesia / methods* Anesthesia, Intravenous Female Hemodynamics Humans Isoflurane / pharmacology* Liver Cirrhosis / surgery Liver Transplantation / physiology* Male Middle Aged Propofol / pharmacology* Retrospective Studies Ventricular Function, Right / drug effects* |
| Chemical | |
Reg. No./Substance:
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2078-54-8/Propofol; 26675-46-7/Isoflurane |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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