| Right internal carotid artery occlusion during intravenous thrombolysis for left middle cerebral artery occlusion. | |
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MedLine Citation:
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PMID: 19110150 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Thrombolysis with recombinant tissue plasminogen activator is the only established treatment for acute ischemic stroke. Recurrent ischemic stroke involving an initially unaffected arterial territory during the course of thrombolysis has been reported but remains exceptionally rare. Here we report a 75-year-old woman with acute left middle cerebral artery occlusion who developed right internal carotid artery occlusion during the last minutes of recombinant tissue plasminogen activator infusion. Although the transthoracic echocardiography did not reveal an intra-atrial thrombus, cardioembolism due to disintegration of a pre-existing thrombus was thought to be the underlying mechanism because the patient had atrial fibrillation. Arterial occlusion due to intraplaque hemorrhage and de novo thrombosis caused by thrombin-mediated platelet aggregation are also discussed as potential mechanisms of arterial occlusion. |
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Authors:
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Gul Yalcin-Cakmakli; Erhan Akpinar; Mehmet Akif Topcuoglu; Turgay Dalkara |
Publication Detail:
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Type: Case Reports; Journal Article |
Journal Detail:
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Title: Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association Volume: 18 ISSN: 1532-8511 ISO Abbreviation: J Stroke Cerebrovasc Dis Publication Date: 2009 Jan |
Date Detail:
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Created Date: 2008-12-26 Completed Date: 2009-02-05 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 9111633 Medline TA: J Stroke Cerebrovasc Dis Country: United States |
Other Details:
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Languages: eng Pagination: 74-7 Citation Subset: IM |
Affiliation:
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Hacettepe University, Faculty of Medicine, Department of Neurology, Ankara, Turkey. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Aged Carotid Artery, Internal* / pathology Carotid Stenosis / chemically induced, etiology*, pathology Cerebral Angiography Diffusion Magnetic Resonance Imaging Embolism / complications Female Fibrinolytic Agents / administration & dosage, adverse effects* Heart Diseases / complications Humans Infarction, Middle Cerebral Artery / drug therapy*, pathology Infusions, Intravenous Recombinant Proteins / administration & dosage Risk Factors Thrombolytic Therapy* Tissue Plasminogen Activator / administration & dosage, adverse effects* Tomography, X-Ray Computed |
| Chemical | |
Reg. No./Substance:
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0/Fibrinolytic Agents; 0/Recombinant Proteins; EC 3.4.21.68/Tissue Plasminogen Activator |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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