Document Detail

Right-hemisphere language dominance in right-handed epileptic patients.
MedLine Citation:
PMID:  6477215     Owner:  NLM     Status:  MEDLINE    
Hemispheric language dominance, as determined by intracarotid amobarbital sodium injections, and handedness, as reflected by writing and drawing preference, were evaluated in a select group of patients with intractable seizures who had documented focal epilepsy originating from one temporal lobe. Of the patients with left temporal lobe seizure focus, an unusually high percentage of right-handed patients (4/26 [15%]) had right hemisphere language dominance. Pathologic findings of the resected temporal lobe in these patients revealed microscopic damage (hippocampal sclerosis) of the hippocampus in three of three cases; one patient also had a small hamartoma in the midtemporal gyrus. We hypothesize that crossed dominance resulted from disruption by epileptiform activity during early development of selective areas of the left hemisphere.
R Rausch; G O Walsh
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Publication Detail:
Type:  Journal Article; Research Support, U.S. Gov't, P.H.S.    
Journal Detail:
Title:  Archives of neurology     Volume:  41     ISSN:  0003-9942     ISO Abbreviation:  Arch. Neurol.     Publication Date:  1984 Oct 
Date Detail:
Created Date:  1984-10-24     Completed Date:  1984-10-24     Revised Date:  2007-11-14    
Medline Journal Info:
Nlm Unique ID:  0372436     Medline TA:  Arch Neurol     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  1077-80     Citation Subset:  AIM; IM    
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MeSH Terms
Brain / physiopathology
Child, Preschool
Dominance, Cerebral*
Epilepsy / pathology,  physiopathology*,  psychology,  radiography
Grant Support

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