| Right heart thrombus-in-transit with pulmonary embolism in a patient with primary hypercoagulable state. | |
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MedLine Citation:
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PMID: 20690100 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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A 25 year-old female with a history of Caesarian section ten weeks ago presented with symptoms suggestive of pulmonary embolism. Transthoracic echocardiography revealed a free-floating large thrombus traversing the right atrial cavity. Transesophageal echocardiography confirmed the presence of an unattached thrombus that originated from the most proximal part of the inferior vena cava. Multi-slice computed tomography of the chest and abdomen revealed the thrombus to start from the intra-hepatic part of the inferior vena cava and extend through the right atrium. It also demonstrated multiple thrombi in the pulmonary vasculature, the largest being in the right main pulmonary artery and its lower lobe branch. The patient was triaged for surgical embolectomy under cardio-pulmonary bypass. Follow-up trans-thoracic and transesophageal echocardiography confirmed adequate removal of the thrombus. By genetic examination, she proved to have factor V 'Leiden' gene and two thrombophilia genes, all of which were positive in the heterozygous state. She had also a high serum homocysteine. |
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Authors:
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Inas I Eweda; Sameh Samir; Osama Abbas; Ghada M El-Gohary; Wail Nammas |
Publication Detail:
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Type: Case Reports; Journal Article |
Journal Detail:
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Title: Cardiology journal Volume: 17 ISSN: 1897-5593 ISO Abbreviation: Cardiol J Publication Date: 2010 |
Date Detail:
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Created Date: 2010-08-06 Completed Date: 2010-11-22 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 101392712 Medline TA: Cardiol J Country: Poland |
Other Details:
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Languages: eng Pagination: 408-11 Citation Subset: IM |
Affiliation:
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Cardiology Department, Faculty of Medicine, Ain Shams University, Abbassia, Cairo, Egypt. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Biological Markers
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blood Cardiopulmonary Bypass DNA Mutational Analysis Echocardiography, Transesophageal Embolectomy Factor V / genetics Female Heart Diseases / diagnosis, etiology*, surgery Homocysteine / blood Humans Methylenetetrahydrofolate Reductase (NADPH2) / genetics Middle Aged Mutation Pulmonary Embolism / diagnosis, etiology*, surgery Thrombophilia / blood, complications*, genetics Thrombosis / diagnosis, etiology*, surgery Tomography, X-Ray Computed Treatment Outcome Up-Regulation |
| Chemical | |
Reg. No./Substance:
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0/Biological Markers; 0/factor V Leiden; 454-28-4/Homocysteine; 9001-24-5/Factor V; EC 1.5.1.20/Methylenetetrahydrofolate Reductase (NADPH2) |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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