Document Detail


Right gastric artery embolization prior to treatment with yttrium-90 microspheres.
MedLine Citation:
PMID:  17031727     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
PURPOSE: Intra-arterial infusion of yttrium-90 microspheres is a form of radiation treatment for unresectable hepatic neoplasms. Misdeposition of particles in the gastroduodenal area such as the right gastric artery (RGA) may occur with serious consequences. We present a series of patients who underwent a detailed vascular study followed by RGA embolization. Special emphasis is placed on anatomic variations and technical considerations. METHODS: In a 1 year period, 27 patients were treated. Initial vascular evaluation was performed, with careful attention to anatomic variants or extrahepatic arterial supply, especially to the gastroduodenal area. Embolization of such arteries was planned if needed. RGA embolization was performed antegradely from the hepatic artery or retrogradely via the left gastric artery (LGA). Postprocedural follow-up included clinical interview and gastroscopy if necessary. RESULTS: RGA embolization was performed in 9 patients presenting with primary (n = 3) or metastatic liver tumors (n = 6). Six patients underwent antegrade RGA embolization and 3 had embolization done retrogradely via the LGA. Retrograde access was chosen for anatomic reasons. None of the patients complained of gastroduodenal symptoms. CONCLUSION: RGA embolization can help minimize the gastroduodenal deposition of radioactive particles. RGA embolization should routinely be carried out. The procedure can be performed, with similar technical success, by both anterograde and retrograde approaches.
Authors:
Octavio Cosin; Jose Ignacio Bilbao; Sergio Alvarez; Esther de Luis; Alberto Alonso; Antonio Martinez-Cuesta
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Publication Detail:
Type:  Clinical Trial; Journal Article    
Journal Detail:
Title:  Cardiovascular and interventional radiology     Volume:  30     ISSN:  0174-1551     ISO Abbreviation:  Cardiovasc Intervent Radiol     Publication Date:    2007 Jan-Feb
Date Detail:
Created Date:  2006-12-04     Completed Date:  2007-03-06     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8003538     Medline TA:  Cardiovasc Intervent Radiol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  98-103     Citation Subset:  IM    
Affiliation:
Departamento de Radiologia, Clinica Universitaria de Navarra, Avd PIO XII 36, Pamplona 31008, Navarra, Spain.
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MeSH Terms
Descriptor/Qualifier:
Antineoplastic Agents / therapeutic use
Breast Neoplasms / pathology*
Carcinoma, Hepatocellular / pathology,  radiotherapy*,  secondary
Colorectal Neoplasms / pathology*
Embolization, Therapeutic / methods*
Female
Follow-Up Studies
Hepatic Artery / radiography
Humans
Infusions, Intra-Arterial / methods
Liver Neoplasms / pathology,  radiotherapy*,  secondary
Male
Microspheres
Middle Aged
Neuroendocrine Tumors / pathology*
Stomach / blood supply*
Treatment Outcome
Yttrium Radioisotopes / therapeutic use
Chemical
Reg. No./Substance:
0/Antineoplastic Agents; 0/Yttrium Radioisotopes

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