Document Detail

Right atrial size relates to right ventricular end-diastolic pressure in an adult population with congenital heart disease.
MedLine Citation:
PMID:  21175780     Owner:  NLM     Status:  In-Data-Review    
Aim: Noninvasive markers of right ventricular (RV) diastolic dysfunction are limited by their lack of reproducibility and accuracy. We tested the hypothesis that right atrial (RA) size measured by echocardiography was correlated to invasive parameters of RV diastolic filling. Methods and Results: We studied 31 consecutive adult patients with congenital heart disease. From 2D echocardiography images, we measured maximal RA long-axis and short-axis lengths, area and volume. We compared each of these measures to right ventricular end-diastolic pressure (RVEDP) and mean right atrial pressure (mRAP) measured by right heart catheterization. RA long-axis, short-axis, area, and volume correlated significantly with RVEDP (r = 0.78, P < 0.001; r = 0.61, P < 0.001; r = 0.79, P < 0.001; and r = 0.75, P < 0.001, respectively) and mRAP (r = 0.66, P < 0.001; r = 0.56, P = 0.002; r = 0.70, P < 0.001; r = 0.68, P < 0.001, respectively). Single cut points for each echocardiographic parameter demonstrated reasonable accuracy to rule-in and rule-out RVEDP ≥7 mm Hg (sensitivity = 74%, specificity = 82%, positive LR = 4.1, negative LR = 0.32 for RA long-axis of 49 mm; sensitivity = 89%, specificity = 82%, positive LR = 4.9, negative LR = 0.12 for RA area of 14 cm(2) ; sensitivity = 89%, specificity = 82%, positive LR = 4.9, negative LR = 0.13 for RA volume of 37 mL). Conclusion: RA size measured by echocardiography is strongly correlated to invasive parameters of RV diastolic filling and predicts high RV end-diastolic pressure. (Echocardiography 2011;28:109-116).
Doan Hoa Do; Judith Therrien; Ariane Marelli; Giuseppe Martucci; Jonathan Afilalo; Igal A Sebag
Publication Detail:
Type:  Journal Article     Date:  2010-12-22
Journal Detail:
Title:  Echocardiography (Mount Kisco, N.Y.)     Volume:  28     ISSN:  1540-8175     ISO Abbreviation:  Echocardiography     Publication Date:  2011 Jan 
Date Detail:
Created Date:  2011-01-24     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8511187     Medline TA:  Echocardiography     Country:  United States    
Other Details:
Languages:  eng     Pagination:  109-16     Citation Subset:  IM    
Copyright Information:
© 2010, Wiley Periodicals, Inc.
Echocardiography Laboratory, Division of Cardiology, Sir Mortimer B. Davis-Jewish General Hospital, Montreal, Canada McGill Adult Unit for Congenital Heart Disease Excellence, McGill University Health Center, Montreal, Canada Department of Medicine, McGill University, Montreal, Canada Department of Medicine, Division of Cardiology, Centre Hospitalier Universitaire de Sherbrooke, Sherbrooke University, Sherbrooke, Canada.
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