Document Detail

Right Ventricular Infarction.
MedLine Citation:
PMID:  11242556     Owner:  NLM     Status:  Publisher    
Right ventricular (RV) ischemia occurs in a substantial proportion of patients with acute inferior myocardial infarction (MI), and may result in severe hemodynamic compromise. This defines a high-risk subset of patients with a mortality rate of 25% to 30%, as opposed to an overall mortality rate of approximately 6% patients with inferior MI without right ventricular infarction (RVI). Early recognition of RV ischemic dysfunction is of great importance in inferior MI with clinical evidence of low cardiac output, because the therapeutic approaches are very different from that for cardiogenic shock resulting predominantly from severe left ventricular (LV) failure. Management of RV ischemic dysfunction includes maintenance of RV preload with volume loading and maintenance of atrioventricular synchrony, inotropic support, and reduction of RV afterload in the setting of LV dysfunction. Reperfusion therapy should be initiated in patients with RV ischemic dysfunction. Though the RV appears to be relatively resistant to infarction and has a remarkable ability to recover even after prolonged occlusion, successful reperfusion of the right coronary artery and major RV branches rapidly improves RV ejection fraction and hemodynamic status, and decreases in-hospital mortality and morbidity.
Soo-Teik Lim; James A. Goldstein
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Publication Detail:
Journal Detail:
Title:  Current treatment options in cardiovascular medicine     Volume:  3     ISSN:  1534-3189     ISO Abbreviation:  Curr Treat Options Cardiovasc Med     Publication Date:  2001 Apr 
Date Detail:
Created Date:  2001-Mar-9     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9815942     Medline TA:  Curr Treat Options Cardiovasc Med     Country:  -    
Other Details:
Languages:  ENG     Pagination:  95-101     Citation Subset:  -    
National Heart Center of Singapore, 17, Third Hospital Avenue, Singapore 168752.
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