Document Detail

Rickets in premature infants receiving parenteral nutrition: a case report and review of the literature.
MedLine Citation:
PMID:  6808176     Owner:  NLM     Status:  MEDLINE    
There is a multifactorial etiology for rickets in premature infants receiving total parenteral nutrition. As an example of this, we describe a premature infant fed almost exclusively parenterally for the first 8 months of life who developed biochemical and radiologic evidence of rickets despite receiving vitamin D, calcium, and phosphorus at presently recommended levels. From our experience and a review of previous literature, there appears to be considerable uncertainty regarding the intravenous requirements of calcium, phosphorus, and vitamin D, particularly in low-birth weight infants. Therefore, measurements of serum 25-hydroxyvitamin D levels, vitamin D, and mineral intakes, and calcium and phosphorus excretion might be clinically useful for monitoring premature infants receiving total parenteral nutrition. Further research delineating more precisely the vitamin D, calcium, and phosphorus requirements of such infants is also suggested.
C L Kien; C Browning; J Jona; R J Starshak
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  JPEN. Journal of parenteral and enteral nutrition     Volume:  6     ISSN:  0148-6071     ISO Abbreviation:  JPEN J Parenter Enteral Nutr     Publication Date:    1982 Mar-Apr
Date Detail:
Created Date:  1982-09-17     Completed Date:  1982-09-17     Revised Date:  2007-02-21    
Medline Journal Info:
Nlm Unique ID:  7804134     Medline TA:  JPEN J Parenter Enteral Nutr     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  152-6     Citation Subset:  IM    
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MeSH Terms
Calcium / administration & dosage
Infant, Newborn
Infant, Newborn, Diseases / etiology*
Infant, Premature*
Parenteral Nutrition / adverse effects*
Parenteral Nutrition, Total / adverse effects*
Phosphorus / administration & dosage
Rickets / etiology*
Vitamin D / administration & dosage
Reg. No./Substance:
1406-16-2/Vitamin D; 7440-70-2/Calcium; 7723-14-0/Phosphorus

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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