Document Detail


Richter Syndrome and Brain Involvement: Low-Grade Lymphoma Relapsing as Cerebral High-Grade Lymphoma.
MedLine Citation:
PMID:  22156510     Owner:  NLM     Status:  Publisher    
Abstract/OtherAbstract:
Richter syndrome (RS) describes the development of high-grade non-Hodgkin's lymphoma (NHL) from low-grade NHL. RS isolated to the brain is very rare and has a poor prognosis. We describe the cases of high-grade large B-cell diffuse NHL in a 56-year-old male with chronic lymphocytic leukemia and in a 71-year-old female with previously unknown low-grade NHL, both with initial appearance of neurological symptoms. This report extends the literature of central nervous system RS and particularly highlights the importance of a thorough diagnostic evaluation of patients with low-grade NHL presenting with neurological symptoms.
Authors:
Moritz Stuplich; Karin Mayer; Young Kim; Sharmilan Thanendrarajan; Matthias Simon; Niklas Schäfer; Martin Glas; Ingo G H Schmidt-Wolf; Ulrich Herrlinger
Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2011-12-10
Journal Detail:
Title:  Acta haematologica     Volume:  127     ISSN:  1421-9662     ISO Abbreviation:  -     Publication Date:  2011 Dec 
Date Detail:
Created Date:  2011-12-13     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0141053     Medline TA:  Acta Haematol     Country:  -    
Other Details:
Languages:  ENG     Pagination:  93-95     Citation Subset:  -    
Copyright Information:
Copyright © 2011 S. Karger AG, Basel.
Affiliation:
Department of Neurology, Division of Clinical Neurooncology, University of Bonn Medical Center, Bonn, Germany.
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