Document Detail

Rhythm management in atrial fibrillation--with a primary emphasis on pharmacological therapy: Part 2.
MedLine Citation:
PMID:  9584306     Owner:  NLM     Status:  MEDLINE    
Atrial fibrillation (AF) is the most common, sustained, symptomatic tachyarrhythmia that clinicians are called upon to manage. Management strategies include ventricular rate control coupled with anticoagulation, versus restoration and maintenance of sinus rhythm. Rate control may be achieved pharmacologically, with agents that impair AV nodal conduction directly and/or by increasing parasympathetic/sympathetic balance, or by modifying or ablating the AV nodal region anatomically. Rhythm control may be achieved by electrical or pharmacological conversion followed by maintenance of sinus rhythm by pharmacological (or occasionally ablative) therapies. This article will present current approaches to rate and rhythm control issues in AF. Part 1, published previously, dealt with rate control. Part 2, the current article, details approaches to the restoration of sinus rhythm by electrical and pharmacological means. The former may use transthoracic or catheter-based energy delivery systems. The latter may use intravenous or oral drug approaches. Part 3, to be published in a subsequent edition of PACE will deal with the maintenance of sinus rhythm.
C Costeas; J Kassotis; M Blitzer; J A Reiffel
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Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  Pacing and clinical electrophysiology : PACE     Volume:  21     ISSN:  0147-8389     ISO Abbreviation:  Pacing Clin Electrophysiol     Publication Date:  1998 Apr 
Date Detail:
Created Date:  1998-07-02     Completed Date:  1998-07-02     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  7803944     Medline TA:  Pacing Clin Electrophysiol     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  742-52     Citation Subset:  IM    
Department of Medicine, Columbia University, New York, New York, USA.
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MeSH Terms
Anti-Arrhythmia Agents / adverse effects,  therapeutic use*
Atrial Fibrillation / drug therapy,  physiopathology,  therapy*
Defibrillators, Implantable
Electric Countershock
Heart Rate
Reg. No./Substance:
0/Anti-Arrhythmia Agents

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