| Rhombencephalitis as an Initial Manifestation of Primary Sjögren's Syndrome: A Case Report and Review of the Literatures. | |
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MedLine Citation:
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PMID: 21249593 Owner: NLM Status: Publisher |
Abstract/OtherAbstract:
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Purpose: We present a case report and a comprehensive review of the literature concerning aseptic meningoencephalitis and Sjögren's syndrome (SS). Case report: We report a 44-year-old woman of primary SS with initial presentation of aseptic meningoencephalitis and a reversible magnetic resonance image (MRI) lesion in the medulla. The diagnosis of primary SS based on ocular dryness, lacrimal hyposecretion, secretory and excretory dysfunction from sialocintigraphy, and positive anti-SS-A antibodies. Corticosteroid and cyclophosphamide therapies reversed the neurological deficits and the MRI lesion. Conclusion: Primayr SS may have variable manifestations in the central nervous system which may precede the classic sicca symptoms. SS should be investigated in cases of aseptic meningoencephalitis even without clinical signs of xerostomia or xerophthalmia. MRI is useful indemostrating brain lesions and in evaluating treatment efficacy of the SS. |
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Authors:
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San-Feng Chen; Ming-Jang Chiu; Jen-Jen Su |
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Publication Detail:
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Type: JOURNAL ARTICLE Date: 2011-1-18 |
Journal Detail:
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Title: Acta neurologica Taiwanica Volume: - ISSN: 1028-768X ISO Abbreviation: - Publication Date: 2011 Jan |
Date Detail:
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Created Date: 2011-1-20 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 9815355 Medline TA: Acta Neurol Taiwan Country: - |
Other Details:
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Languages: ENG Pagination: - Citation Subset: - |
Affiliation:
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Department of Neurology, National Taiwan University Hospital. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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