Document Detail


Rhodotorula mucilaginosa catheter-related fungemia in a patient with sickle cell disease: case presentation and literature review.
MedLine Citation:
PMID:  17330692     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Rhodotorula mucilaginosa (formerly Rhodotorula rubra) is a ubiquitous, environmental, urease-positive yeast that does not ferment sugars and can assimilate various carbohydrates. Characterized by the salmon-pink to coral-red color of its colonies, Rhodotorula mucilaginosa can disseminate and cause significant disease. We present a case of sustained Rhodotorula mucilaginosa catheter-related fungemia in a patient with sickle cell anemia who refused removal of the implanted port. The patient remained clinically stable, with blood cultures persistently growing Rhodotorula mucilaginosa, despite appropriate antifungal therapy. An extensive literature review revealed a wide range of clinical manifestations in immunocompromised patients. Susceptibility patterns to different antifungal agents and therapeutic considerations are thoroughly discussed. Rhodotorula mucilaginosa can be a significant, recalcitrant pathogen in immunocompromised patients and prompt treatment should be instituted.
Authors:
Dionissios Neofytos; David Horn; Joseph A De Simone
Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Southern medical journal     Volume:  100     ISSN:  0038-4348     ISO Abbreviation:  South. Med. J.     Publication Date:  2007 Feb 
Date Detail:
Created Date:  2007-03-02     Completed Date:  2007-03-15     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0404522     Medline TA:  South Med J     Country:  United States    
Other Details:
Languages:  eng     Pagination:  198-200     Citation Subset:  AIM; IM    
Affiliation:
Division of Infectious Diseases and Environmental Medicine, Thomas Jefferson University Hospital, 125 South 9th Street, Suite 403, Philadelphia, PA 19107, USA. dionissios.neofytos@mail.tju.edu
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MeSH Terms
Descriptor/Qualifier:
Adult
Anemia, Sickle Cell / therapy*
Antifungal Agents / therapeutic use
Catheterization, Central Venous / adverse effects*,  instrumentation
Catheters, Indwelling / adverse effects,  microbiology*
Follow-Up Studies
Fungemia / drug therapy,  etiology*,  microbiology
Humans
Male
Rhodotorula / isolation & purification*
Subclavian Vein
Chemical
Reg. No./Substance:
0/Antifungal Agents
Comments/Corrections
Comment In:
South Med J. 2007 Feb;100(2):130-1   [PMID:  17330678 ]

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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