| Rhodotorula mucilaginosa catheter-related fungemia in a patient with sickle cell disease: case presentation and literature review. | |
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MedLine Citation:
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PMID: 17330692 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Rhodotorula mucilaginosa (formerly Rhodotorula rubra) is a ubiquitous, environmental, urease-positive yeast that does not ferment sugars and can assimilate various carbohydrates. Characterized by the salmon-pink to coral-red color of its colonies, Rhodotorula mucilaginosa can disseminate and cause significant disease. We present a case of sustained Rhodotorula mucilaginosa catheter-related fungemia in a patient with sickle cell anemia who refused removal of the implanted port. The patient remained clinically stable, with blood cultures persistently growing Rhodotorula mucilaginosa, despite appropriate antifungal therapy. An extensive literature review revealed a wide range of clinical manifestations in immunocompromised patients. Susceptibility patterns to different antifungal agents and therapeutic considerations are thoroughly discussed. Rhodotorula mucilaginosa can be a significant, recalcitrant pathogen in immunocompromised patients and prompt treatment should be instituted. |
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Authors:
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Dionissios Neofytos; David Horn; Joseph A De Simone |
Publication Detail:
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Type: Case Reports; Journal Article |
Journal Detail:
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Title: Southern medical journal Volume: 100 ISSN: 0038-4348 ISO Abbreviation: South. Med. J. Publication Date: 2007 Feb |
Date Detail:
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Created Date: 2007-03-02 Completed Date: 2007-03-15 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 0404522 Medline TA: South Med J Country: United States |
Other Details:
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Languages: eng Pagination: 198-200 Citation Subset: AIM; IM |
Affiliation:
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Division of Infectious Diseases and Environmental Medicine, Thomas Jefferson University Hospital, 125 South 9th Street, Suite 403, Philadelphia, PA 19107, USA. dionissios.neofytos@mail.tju.edu |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adult Anemia, Sickle Cell / therapy* Antifungal Agents / therapeutic use Catheterization, Central Venous / adverse effects*, instrumentation Catheters, Indwelling / adverse effects, microbiology* Follow-Up Studies Fungemia / drug therapy, etiology*, microbiology Humans Male Rhodotorula / isolation & purification* Subclavian Vein |
| Chemical | |
Reg. No./Substance:
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0/Antifungal Agents |
| Comments/Corrections | |
Comment In:
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South Med J. 2007 Feb;100(2):130-1
[PMID:
17330678
]
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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