Document Detail


Rho GTPases and cell cycle control.
MedLine Citation:
PMID:  16574576     Owner:  NLM     Status:  In-Data-Review    
Abstract/OtherAbstract:
Members of the Rho family of small GTPases are crucial regulators of biological responses in eukaryotic cells, including cytoskeletal dynamics, cell motility and cell cycle progression. In the present review, we summarize our current understanding of the role of Rho proteins in cell cycle control, highlighting the contribution of specific members of the Rho family and their downstream targets to the regulation of key elements from the core cell cycle machinery, mostly involved in the G1/S transition.
Authors:
Priam Villalonga; Anne J Ridley
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Growth factors (Chur, Switzerland)     Volume:  Suppl     ISSN:  0897-7194     ISO Abbreviation:  Growth Factors     Publication Date:  2006  
Date Detail:
Created Date:  2006-03-31     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9000468     Medline TA:  Growth Factors     Country:  England    
Other Details:
Languages:  eng     Pagination:  1     Citation Subset:  IM    
Affiliation:
Ludwig Institute for Cancer Research and Department of Biochemistry and Molecular Biology, University College London, London, UK.
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