Document Detail


Rhinovirus and coronavirus infections.
MedLine Citation:
PMID:  17458772     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Rhinoviruses and coronaviruses cause the majority of common colds and play a part in more serious respiratory illnesses that lead to increased morbidity and mortality. Patients who are infants or elderly, have asthma or chronic obstructive pulmonary disease (COPD), or are immunosuppressed have increased frequency of rhinovirus-related respiratory complications. Newer diagnostic tests such as reverse transcriptase polymerase chain reaction (RT-PCR) have greatly expanded our understanding of the importance of these respiratory viruses. Although there are no currently approved antiviral agents for clinical use, our increased understanding of the virus-host interaction should lead to new intervention strategies.
Authors:
Stephen B Greenberg
Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  Seminars in respiratory and critical care medicine     Volume:  28     ISSN:  1069-3424     ISO Abbreviation:  Semin Respir Crit Care Med     Publication Date:  2007 Apr 
Date Detail:
Created Date:  2007-04-26     Completed Date:  2007-06-13     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9431858     Medline TA:  Semin Respir Crit Care Med     Country:  United States    
Other Details:
Languages:  eng     Pagination:  182-92     Citation Subset:  IM    
Affiliation:
Department of Medicine, Baylor College of Medicine, Houston, Texas 77030, USA. stepheng@bcm.edu
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MeSH Terms
Descriptor/Qualifier:
Acute Disease
Antiviral Agents / therapeutic use
Asthma / complications
Common Cold / complications,  drug therapy
Coronavirus* / genetics
Coronavirus Infections* / complications,  drug therapy,  epidemiology
Cystic Fibrosis / complications
Humans
Immunocompromised Host
Otitis Media / complications
Picornaviridae Infections* / complications,  drug therapy,  epidemiology
Pulmonary Disease, Chronic Obstructive / complications
Reverse Transcriptase Polymerase Chain Reaction
Rhinovirus* / genetics
Sinusitis / complications
Chemical
Reg. No./Substance:
0/Antiviral Agents

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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