Document Detail


Rhinofacial conidiobolomycosis caused by Conidiobolus coronatus in a Chinese rice farmer.
MedLine Citation:
PMID:  19422524     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
We provide the first report of rhinofacial conidiobolomycosis caused by Conidiobolus coronatus in China. The patient was a 36-year-old male rice farmer from Jiang Xi province who presented with diffuse swelling with classical centrofacial distribution and involvement of the right paranasal sinuses. Histopathology showed granulomas with hyphae surrounded by an eosinophilic sheath (Splendore-Hoeppli phenomenon). Culture of biopsy specimens on Sabouraud's dextrose agar led to the growth of fungi with microscopically visible conidiophores and terminal spherical conidia (primary conidium), with multiple secondary conidia and villose conidia. The patient was successfully treated with combination therapy, primarily itraconazole and terbinafine. We conclude with a brief literature review of the epidemiology of conidiobolomycosis.
Authors:
Xiumin Yang; Yadi Li; Xiaoqian Zhou; Yuxin Wang; Suying Geng; Honggang Liu; Qingwen Yang; Xinxin Lu; Masataro Hiruma; Takashi Sugita; Shigaku Ikeda; Hideoki Ogawa
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Publication Detail:
Type:  Case Reports; Letter; Review     Date:  2009-05-05
Journal Detail:
Title:  Mycoses     Volume:  53     ISSN:  1439-0507     ISO Abbreviation:  Mycoses     Publication Date:  2010 Jul 
Date Detail:
Created Date:  2010-07-20     Completed Date:  2010-10-19     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8805008     Medline TA:  Mycoses     Country:  Germany    
Other Details:
Languages:  eng     Pagination:  369-73     Citation Subset:  IM    
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MeSH Terms
Descriptor/Qualifier:
Adult
Agriculture
Antifungal Agents / therapeutic use
Asian Continental Ancestry Group
China
Conidiobolus / cytology,  growth & development,  isolation & purification*
Culture Media / chemistry
Drug Therapy, Combination
Face / pathology
Granuloma / pathology
Histocytochemistry
Humans
Hyphae / cytology
Itraconazole / therapeutic use
Male
Mycology / methods
Naphthalenes / therapeutic use
Oryza sativa
Paranasal Sinuses / microbiology*,  pathology*
Zygomycosis / diagnosis*,  microbiology
Chemical
Reg. No./Substance:
0/Antifungal Agents; 0/Culture Media; 0/Naphthalenes; 84625-61-6/Itraconazole; 91161-71-6/terbinafine

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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