| Rhesus disease: postnatal management and outcome. | |
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MedLine Citation:
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PMID: 10485296 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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The incidence of rhesus haemolytic disease has been markedly reduced. Affected infants who have had intrauterine transfusions suffer a late hyporegenerative anaemia. Postnatal haemolysis and hence treatment for hyperbilirubinaemia is less commonly needed. Optimal phototherapy reduces the need for postnatal exchange transfusions, but data on the efficacy of inhibitors of bilirubin production such as haem oxygenase inhibitors or immunoglobulin are less secure. Even hydropic infants have less than 20% mortality and bilirubin encephalopathy is uncommon. There is, however, very limited information on the long-term outcome of infants with rhesus haemolytic disease. Multicentre collaboration is required to test strategies to improve the management of affected individuals further and to provide meaningful data on their prognosis. |
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Authors:
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A Greenough |
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Publication Detail:
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Type: Journal Article; Review |
Journal Detail:
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Title: European journal of pediatrics Volume: 158 ISSN: 0340-6199 ISO Abbreviation: Eur. J. Pediatr. Publication Date: 1999 Sep |
Date Detail:
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Created Date: 1999-10-21 Completed Date: 1999-10-21 Revised Date: 2005-11-16 |
Medline Journal Info:
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Nlm Unique ID: 7603873 Medline TA: Eur J Pediatr Country: GERMANY |
Other Details:
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Languages: eng Pagination: 689-93 Citation Subset: IM |
Affiliation:
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Children Nationwide Regional Neonatal Intensive Care Centre, King's College Hospital, London, UK. anne.greenough@kcl.ac.uk |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Blood Transfusion Blood Transfusion, Intrauterine Female Humans Immunoglobulins, Intravenous / therapeutic use Infant, Newborn Male Phototherapy Pregnancy Rh Isoimmunization / complications, mortality, therapy* |
| Chemical | |
Reg. No./Substance:
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0/Immunoglobulins, Intravenous |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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