Document Detail


Rheos: an implantable carotid sinus stimulation device for the nonpharmacologic treatment of resistant hypertension.
MedLine Citation:
PMID:  21285662     Owner:  NLM     Status:  In-Data-Review    
Abstract/OtherAbstract:
Hypertension is a highly prevalent disorder in the United States. Of particular concern is resistant hypertension, which by definition is hypertension that cannot be adequately treated by conventional 3-drug regimens. The Rheos Baroreflex Hypertension Therapy System is a new implantable device that can treat patients with hypertension resistant to multidrug therapy, by activating the carotid baroreflex through electrical stimulation of the carotid sinus wall. Recent studies in both normotensive and hypertensive canine models have demonstrated sustained and clinically relevant reductions in arterial pressure and sympathetic activity with prolonged baroreflex activation. Clinical trials designed to evaluate the efficacy and safety of this therapy in patients with treatment resistant hypertension, are now ongoing in both Europe and the United States.
Authors:
Maria M Ng; Domenic A Sica; William H Frishman
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Cardiology in review     Volume:  19     ISSN:  1538-4683     ISO Abbreviation:  Cardiol Rev     Publication Date:    2011 Mar-Apr
Date Detail:
Created Date:  2011-02-02     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9304686     Medline TA:  Cardiol Rev     Country:  United States    
Other Details:
Languages:  eng     Pagination:  52-7     Citation Subset:  IM    
Affiliation:
From the *Department of Medicine, Ronald Reagan-UCLA Medical Center, UCLA School of Medicine, Los Angeles, CA; †Department of Medicine, Virginia Commonwealth University Health System, Richmond, VA; and ‡Department of Medicine, New York Medical College/Westchester Medical Center, Valhalla, NY.
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