Document Detail


Rhabdomyosarcoma of the trachea: first reported case treated with proton beam therapy.
MedLine Citation:
PMID:  22892225     Owner:  NLM     Status:  In-Data-Review    
Abstract/OtherAbstract:
Objective: We report a case of rhabdomyosarcoma of the trachea in a 14-month-old child, and we present the first reported use of proton beam therapy for this tumour. Case report: A 14-month-old girl presented acutely with a seven-day history of biphasic stridor. Emergency endoscopic debulking of a posterior tracheal mass was undertaken. Histological examination revealed an embryonal rhabdomyosarcoma with anaplasia. Multimodality therapy with surgery and chemotherapy was administered in the UK, and proton beam therapy in the USA. Conclusion: Only three cases of rhabdomyosarcoma of the trachea have previously been reported in the world literature. This is the first reported case of treatment of this tumour with proton beam therapy. Compared with conventional radiotherapy, proton beam therapy may confer improved long-term outcome in children, with benefits including reduced irradiation of the spinal cord.
Authors:
R Exley; J M Bernstein; B Brennan; M P Rothera
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  The Journal of laryngology and otology     Volume:  126     ISSN:  1748-5460     ISO Abbreviation:  J Laryngol Otol     Publication Date:  2012 Sep 
Date Detail:
Created Date:  2012-08-15     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8706896     Medline TA:  J Laryngol Otol     Country:  England    
Other Details:
Languages:  eng     Pagination:  966-9     Citation Subset:  AIM; IM    
Affiliation:
Department of Head and Neck Surgical Oncology, Christie Hospital, Manchester, UK.
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