Document Detail


Rhabdomyolysis induced by Pseudomonas aeruginosa sepsis.
MedLine Citation:
PMID:  18500617     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
We describe advanced hemodynamic insufficiency and remarkably high myoglobinemia in a 77-year-old man who was admitted to the intensive care unit after total aortic arch replacement. Serum myoglobin showed an unusually high value (peak value, 155,030 ng x ml(-1)). The patient died of sepsis and untreatable metabolic acidosis. Pseudomonas aeruginosa was detected in blood culture specimens after his death. On histopathological examination, dense congregations of gram-negative bacilli were present in clots in blood vessels, while congregations of gram-negative bacilli around the circumference of small blood vessels were particularly apparent in every specimen examined. Moreover, a generalized breakdown of muscle fibers, consistent with findings of rhabdomyolysis, was observed in muscle tissue throughout the body.
Authors:
Naoya Iguchi; Yuji Fujino; Akinori Uchiyama; Osamu Hirao; Noriyuki Ohta; Takashi Mashimo; Eiichi Morii
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Publication Detail:
Type:  Case Reports; Journal Article     Date:  2008-05-25
Journal Detail:
Title:  Journal of anesthesia     Volume:  22     ISSN:  0913-8668     ISO Abbreviation:  J Anesth     Publication Date:  2008  
Date Detail:
Created Date:  2008-05-26     Completed Date:  2008-10-30     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8905667     Medline TA:  J Anesth     Country:  Japan    
Other Details:
Languages:  eng     Pagination:  173-6     Citation Subset:  IM    
Affiliation:
Intensive Care Unit, Osaka University Hospital, Suita, Osaka, Japan.
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MeSH Terms
Descriptor/Qualifier:
Aged
Fatal Outcome
Humans
Male
Myoglobin / blood
Pseudomonas Infections / complications*
Pseudomonas aeruginosa
Rhabdomyolysis / etiology*,  pathology
Sepsis / complications*,  pathology
Chemical
Reg. No./Substance:
0/Myoglobin

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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