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Rhabdomyolysis caused by an interaction of simvastatin and fusidic acid.
MedLine Citation:
PMID:  21931583     Owner:  NLM     Status:  PubMed-not-MEDLINE    
Abstract/OtherAbstract:
A case of severe rhabdomyolysis caused by an interaction between fusidic acid and simvastatin is described. Fusidic acid significantly reduces the excretion of simvastatin resulting in increased plasma levels thereby increasing the side effect profile. Simvastatin treatment should be temporarily withheld during treatment with fusidic acid.
Authors:
Roselle Herring; Gordon Caldwell; Stuart Wade
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Publication Detail:
Type:  Journal Article     Date:  2009-09-20
Journal Detail:
Title:  BMJ case reports     Volume:  2009     ISSN:  1757-790X     ISO Abbreviation:  BMJ Case Rep     Publication Date:  2009  
Date Detail:
Created Date:  2011-09-20     Completed Date:  2011-11-10     Revised Date:  2012-05-07    
Medline Journal Info:
Nlm Unique ID:  101526291     Medline TA:  BMJ Case Rep     Country:  England    
Other Details:
Languages:  eng     Pagination:  -     Citation Subset:  -    
Affiliation:
Worthing and Southlands NHS Trust, Endocrine and Diabetes, Worthing Hospital, Lyndhurst Road, West Sussex, BN11 2DH, UK.
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