Document Detail


Rhabdomyoblastic Differentiation in Metastatic Melanoma: Making Sense of This Rare but Complex Form of Mimicry.
MedLine Citation:
PMID:  24275885     Owner:  NLM     Status:  Publisher    
Abstract/OtherAbstract:
A case of melanoma with rhabdomyoblastic differentiation is presented in the context of the previously reported cases. The emerging literature seeking to identify the molecular basis of rhabdoid and rhabdomyoblastic differentiation, as well as their poor prognosis, is reviewed. The combination of a diverse range of morphology and the potential for spontaneous primary tumor regression, despite metastasis, makes the accurate diagnosis of melanoma challenging. Histopathology review is often recommended in these cases, as is referral to a specialized cancer center for discussion in a multidisciplinary meeting. Improved recognition of this rare pattern of melanoma morphology may provide the means for omics-based techniques to identify novel therapeutic targets to improve the prognostic outlook for these patients.
Authors:
Daniel J Reilly; Mila Volchek; Jeannette W C Ting; Prue Allan; Michael W Findlay
Related Documents :
8441265 - Choroidal metastasis from primary adenocarcinoma of the esophagus.
14576475 - Signet-ring cell change versus signet-ring cell carcinoma: a comparative analysis.
2828555 - Patterns of epithelial metaplasia in malignant gliomas. i. papillary formations mimicki...
11206355 - Polyarteritis nodosa mimicking polymyalgia rheumatica.
20625745 - Gastric teratoma with predominant nephroblastic elements.
21762055 - Tracheal paraganglioma: a case report.
Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2013-11-25
Journal Detail:
Title:  International journal of surgical pathology     Volume:  -     ISSN:  1940-2465     ISO Abbreviation:  Int. J. Surg. Pathol.     Publication Date:  2013 Nov 
Date Detail:
Created Date:  2013-11-26     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9314927     Medline TA:  Int J Surg Pathol     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  Rare Flowers in the Thyroid Gland: The Case of Small Cell Tumors.
Next Document:  Estimation of Quizalofop Ethyl Residues in Black Gram (Vigna mungo L.) by Gas Liquid Chromatography.