Document Detail

Rhabdoid tumor of the skin.
MedLine Citation:
PMID:  1323543     Owner:  NLM     Status:  MEDLINE    
A tumor in the skin of a 42-year-old man was analyzed by light and electron microscopic study and immunohistochemistry. The tumor cells were large and contained eosinophilic, periodic acid-Schiff (PAS)-positive inclusions in the cytoplasm. Immunohistochemically, the neoplasm was positive for intermediate filaments, cytokeratin, vimentin, desmin, and alpha-1-antichimotrypsin, and negative for S-100 and leukocyte common antigen (LCA). Ultrastructurally, the cytoplasm and cellular processes of the cells were inundated with intermediate filaments, some of which were tightly bundled. Junctional complexes and secretory granules were absent. These features suggest a rhabdoid tumor: a malignant tumor of uncertain origin.
O P Sangueza; C K Meshul; P Sangueza; R Mendoza
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  International journal of dermatology     Volume:  31     ISSN:  0011-9059     ISO Abbreviation:  Int. J. Dermatol.     Publication Date:  1992 Jul 
Date Detail:
Created Date:  1992-09-17     Completed Date:  1992-09-17     Revised Date:  2006-10-30    
Medline Journal Info:
Nlm Unique ID:  0243704     Medline TA:  Int J Dermatol     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  484-7     Citation Subset:  IM    
Department of Pathology, Oregon Health Sciences University School of Medicine, Portland.
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MeSH Terms
Immunoenzyme Techniques
Microscopy, Electron
Neoplasm Invasiveness
Rhabdomyosarcoma / pathology
Skin Neoplasms / pathology*,  ultrastructure
Wilms Tumor / pathology

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