Document Detail


Rh serology--coordinator's report.
MedLine Citation:
PMID:  9018785     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
168 Rh specific monoclonal antibodies (Mabs) were evaluated in 43 laboratories. Red cells from 63 Rh variant phenotype donations were circulated in panels to evaluators. Circulation was organised to ensure adequate duplicate testing. Evaluators were asked to test each Mab at 3 dilutions in two specified techniques against normal phenotype cells, panel cells received and any other Rh variant cells they had available. Results were analysed by expressing the sum of reaction grades for each Mab with each variant cell as a percentage of the sum of reaction grades of that Mab with normal phenotype cells. Reactions with enzyme-treated cells were found to be highly variable between laboratories, and further analysis of these results was not attempted. Anti-D Mabs were sorted into groups which had the same pattern of reactions with different phenotype cells. 24 such patterns were identified, 17 corresponding to previously reported patterns and 7 new ones.
Authors:
M Scott
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Transfusion clinique et biologique : journal de la Société française de transfusion sanguine     Volume:  3     ISSN:  1246-7820     ISO Abbreviation:  Transfus Clin Biol     Publication Date:  1996  
Date Detail:
Created Date:  1997-04-10     Completed Date:  1997-04-10     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  9423846     Medline TA:  Transfus Clin Biol     Country:  FRANCE    
Other Details:
Languages:  eng     Pagination:  333-7     Citation Subset:  IM    
Affiliation:
International Blood Group Reference Laboratory, Bristol, UK.
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MeSH Terms
Descriptor/Qualifier:
Antibodies, Monoclonal*
Erythrocytes / immunology
Humans
Rh-Hr Blood-Group System / immunology*
Serology
Chemical
Reg. No./Substance:
0/Antibodies, Monoclonal; 0/Rh-Hr Blood-Group System

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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