Document Detail

Rh hemolytic disease. Epidemiologic surveillance in the United States, 1968 to 1975.
MedLine Citation:
PMID:  113567     Owner:  NLM     Status:  MEDLINE    
Nationwide surveillance of Rh hemolytic disease of the newborn showed that associated infant mortality decreased from 941 deaths in 1968 to 269 deaths in 1975, or from 2.7 to 0.9 per 10,000 live births. The incidence of Rh hemolytic disease declined from 45 per 10,000 total births in 1970 to 21 per 10,000 in 1975. In 1970, an estimated 16,000 infants were affected, whereas in 1975, the number was 6,000. Several state-based Rh disease surveillance programs reported declining mortality and incidence and increasing use of Rh immune globulin. Rh immune globulin was administered to an estimated 80% of eligible Rh-negative women in 1974, eighty-one percent in 1975, and 82% in 1976. More concerted efforts are needed to determine the frequency of maternal sensitization and to identify and correct gaps in postpartum and postabortion use of Rh immune globulin.
D K Wysowski; J W Flynt; M F Goldberg; F A Connell
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  JAMA     Volume:  242     ISSN:  0098-7484     ISO Abbreviation:  JAMA     Publication Date:  1979 Sep 
Date Detail:
Created Date:  1979-11-21     Completed Date:  1979-11-21     Revised Date:  2014-09-17    
Medline Journal Info:
Nlm Unique ID:  7501160     Medline TA:  JAMA     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  1376-9     Citation Subset:  AIM; IM    
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MeSH Terms
Erythroblastosis, Fetal / epidemiology*,  mortality,  prevention & control
Immunoglobulins / therapeutic use
Infant, Newborn
Rh-Hr Blood-Group System
United States
Reg. No./Substance:
0/Immunoglobulins; 0/Rh-Hr Blood-Group System

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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