Document Detail


Rh alloimmunization: Doppler or amniotic fluid analysis in the prediction of fetal anemia?
MedLine Citation:
PMID:  16900344     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
OBJECTIVE: Compare the results of amniocentesis and those of middle cerebral artery peak systolic velocity to detect anemic fetuses in Rh alloimmunized pregnancies. METHOD: Descriptive observational study involving 99 consecutive Rh-negative pregnancies: 74 alloimmunized patients submitted to amniotic fluid spectrophotometry (group 1) and 25 alloimmunized cases managed with Doppler ultrasonography (group 2). Variables analyzed were the following: need for neonatal transfusion and neonatal hematocrit. RESULT: Neonatal hematocrit was significantly lower and the need for neonatal transfusion was significantly higher in cases managed with spectrophotometry compared to those managed with Doppler. CONCLUSION: Infants managed with Doppler velocimetry had higher hematocrit and less need for neonatal transfusion, suggesting that this non-invasive method of monitoring fetal anemia may best preserve the neonate.
Authors:
Luciano Marcondes Machado Nardozza; Antonio Fernandes Moron; Edward Araujo Júnior; Luiz Camano; Paulo Alexandre Chinen; Maria Regina Torloni
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Publication Detail:
Type:  Comparative Study; Journal Article     Date:  2006-08-10
Journal Detail:
Title:  Archives of gynecology and obstetrics     Volume:  275     ISSN:  0932-0067     ISO Abbreviation:  Arch. Gynecol. Obstet.     Publication Date:  2007 Feb 
Date Detail:
Created Date:  2007-03-05     Completed Date:  2007-10-30     Revised Date:  2007-11-04    
Medline Journal Info:
Nlm Unique ID:  8710213     Medline TA:  Arch Gynecol Obstet     Country:  Germany    
Other Details:
Languages:  eng     Pagination:  107-11     Citation Subset:  IM    
Affiliation:
Obstetrics Department, UNIFESP-EPM, Av. Lopes de Azevedo, 888, São Paulo, SP, 05603-001, Brazil. lunardozza@uol.com.br
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MeSH Terms
Descriptor/Qualifier:
Adolescent
Adult
Amniocentesis*
Anemia / diagnosis*,  etiology,  therapy
Blood Flow Velocity
Blood Transfusion / utilization
Female
Fetal Death / etiology
Fetal Diseases / diagnosis*,  etiology,  therapy
Hematocrit / methods
Humans
Infant, Newborn
Middle Cerebral Artery / physiology,  ultrasonography
Rh Isoimmunization / complications*
Spectrophotometry
Ultrasonography, Doppler*

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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