| Rewritable DNA microarrays. | |
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MedLine Citation:
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PMID: 16478182 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Thiol-terminated single-stranded deoxyribonucleic acids (ssDNA) can be immobilized onto pulsed plasma deposited poly(allylmercaptan) surfaces via disulfide bridge chemistry and are found to readily undergo nucleic acid hybridization. Unlike other methods for oligonucleotide attachment to solid surfaces, this approach is shown to be independent of substrate material or geometry, and amenable to highly efficient rewriting. |
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Authors:
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W C E Schofield; J McGettrick; T J Bradley; J P S Badyal; S Przyborski |
Publication Detail:
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Type: Journal Article; Research Support, Non-U.S. Gov't |
Journal Detail:
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Title: Journal of the American Chemical Society Volume: 128 ISSN: 0002-7863 ISO Abbreviation: J. Am. Chem. Soc. Publication Date: 2006 Feb |
Date Detail:
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Created Date: 2006-02-15 Completed Date: 2006-04-25 Revised Date: 2006-11-15 |
Medline Journal Info:
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Nlm Unique ID: 7503056 Medline TA: J Am Chem Soc Country: United States |
Other Details:
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Languages: eng Pagination: 2280-5 Citation Subset: IM |
Affiliation:
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Department of Chemistry, Science Laboratories, and School of Biological and Biomedical Science, Durham University, Durham DH1 3LE, England, UK. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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DNA, Single-Stranded
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chemistry* Disulfides / chemistry* Nucleic Acid Hybridization Oligonucleotide Array Sequence Analysis / methods* Oligonucleotide Probes / chemistry Spectroscopy, Fourier Transform Infrared Sulfhydryl Compounds / chemistry |
| Chemical | |
Reg. No./Substance:
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0/DNA, Single-Stranded; 0/Disulfides; 0/Oligonucleotide Probes; 0/Sulfhydryl Compounds |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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