| Revisiting fluoxetine (Proxac) and suicidal preoccupations. | |
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MedLine Citation:
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PMID: 7989697 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Several reports were published in the psychiatric literature in 1990 and 1991 documenting fluoxetine (Prozac) causing patients to consider or attempt suicide. During the following 2 years, retrospective studies appeared in the medical literature that seemed to indicate that suicidal preoccupation was not related to the antidepressant fluoxetine (Prozac) but was probably a symptom of the depressive illness. Recent studies have suggested, however, that fluoxetine (Prozac) may in fact lead to suicidal behavior because the drug appears to adversely affect serotonergic neuronal discharge and induce an akathisia-like extrapyramidal reaction. While fluoxetine (Prozac) has a very favorable side effect profile compared to the tricyclic antidepressants, it may cause akathisia and induce a small subset of patients to consider or attempt suicide. |
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Authors:
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M J Tueth |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: The Journal of emergency medicine Volume: 12 ISSN: 0736-4679 ISO Abbreviation: J Emerg Med Publication Date: 1994 Sep-Oct |
Date Detail:
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Created Date: 1995-01-11 Completed Date: 1995-01-11 Revised Date: 2004-11-17 |
Medline Journal Info:
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Nlm Unique ID: 8412174 Medline TA: J Emerg Med Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: 685-7 Citation Subset: IM |
Affiliation:
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Department of Psychiatry, University of Florida, Gainesville 32608. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Akathisia, Drug-Induced
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etiology Depressive Disorder / drug therapy, psychology Fluoxetine / adverse effects* Humans Suicide* / psychology |
| Chemical | |
Reg. No./Substance:
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54910-89-3/Fluoxetine |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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