Document Detail


Revisable criteria for vertebral deformity.
MedLine Citation:
PMID:  8400609     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
In order to study vertebral fractures in various study populations, we earlier prepared a database of vertebral dimensions derived from spinal radiographs of 191 normal women seen regularly over 25 years. In this report we have expanded the range of measurements to include vertebral levels T3 to L5. We report means and standard deviations on anterior and posterior heights, on wedge shape and on heights relative to adjacent vertebrae. When one or both of the latter two quantities are 'far' below the mean, a vertebra is called deformed. We also describe a more flexible way of expressing damage using the number of deformed vertebrae, the degree of deformity of individual vertebrae, or the total damage to the entire spine. In assessing damage we use criteria for deformity adjusted to the limits detected by an experienced diagnostician, replacing an earlier approach based on 95% probability limits of normal variation. The normal women from whom these variations are ascertained are a low-prevalence group with respect to vertebral deformity, with prevalence of 2.8%. When the criteria developed from these women were applied to a moderate-prevalence group (37%) the model had a sensitivity of 97%, a specificity of 89% and an accuracy of 92% as regards the identification of subjects with damaged vertebrae. When used epidemiologically for a moderate-prevalence group the model has a known overestimation of 15%. the model is compared with other schemes for identifying vertebral deformities.
Authors:
K M Davies; R R Recker; R P Heaney
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Publication Detail:
Type:  Journal Article; Research Support, U.S. Gov't, P.H.S.    
Journal Detail:
Title:  Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA     Volume:  3     ISSN:  0937-941X     ISO Abbreviation:  Osteoporos Int     Publication Date:  1993 Sep 
Date Detail:
Created Date:  1993-11-18     Completed Date:  1993-11-18     Revised Date:  2007-11-14    
Medline Journal Info:
Nlm Unique ID:  9100105     Medline TA:  Osteoporos Int     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  265-70     Citation Subset:  IM    
Affiliation:
Department of Medicine, Creighton University, Omaha, Nebraska.
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MeSH Terms
Descriptor/Qualifier:
Adult
Aged
Cohort Studies
Female
Humans
Lumbar Vertebrae / pathology*,  radiography
Middle Aged
Models, Biological*
Premenopause
Sensitivity and Specificity
Thoracic Vertebrae / pathology*,  radiography
Grant Support
ID/Acronym/Agency:
AR 07912/AR/NIAMS NIH HHS; AR 39221/AR/NIAMS NIH HHS

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