Document Detail

Review of reported cholera outbreaks worldwide, 1995-2005.
MedLine Citation:
PMID:  17123999     Owner:  NLM     Status:  MEDLINE    
The global temporal and spatial distribution of cholera is underappreciated, given the lack of surveillance in endemic areas and economic disincentives to report outbreaks. To judge the use of specific novel interventions such as vaccines or anti-secretory agents, we compiled a database and analyzed cholera reports from the Program for Monitoring Emerging Diseases from 1995 to 2005. Of the 632 reports meeting the search criteria, 66% originated in Sub-Saharan Africa, followed by 16.8% from Southeast Asia. Reported outbreaks in Africa tended to be larger in size. The most common risk factors were water source contamination, heavy rainfall and flooding, and population dislocation. While cholera reporting is sub-optimal, this review provides a detailed sub-national quantification of cholera, identifies foci of endemicity in Africa, and describes risk factors by region. We highlight the need for more extensive outbreak reporting to justify investments in new interventions.
David C Griffith; Louise A Kelly-Hope; Mark A Miller
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Publication Detail:
Type:  Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Review    
Journal Detail:
Title:  The American journal of tropical medicine and hygiene     Volume:  75     ISSN:  0002-9637     ISO Abbreviation:  Am. J. Trop. Med. Hyg.     Publication Date:  2006 Nov 
Date Detail:
Created Date:  2006-11-24     Completed Date:  2007-01-08     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0370507     Medline TA:  Am J Trop Med Hyg     Country:  United States    
Other Details:
Languages:  eng     Pagination:  973-7     Citation Subset:  AIM; IM    
Fogarty International Center, National Institutes of Health, Bethesda, Maryland 20892, USA.
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MeSH Terms
Cholera / epidemiology*,  prevention & control,  therapy,  transmission
Disease Outbreaks*
Population Surveillance / methods*
Vibrio cholerae*
World Health*

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