| Review on recent and advanced applications of monoliths and related porous polymer gels in micro-fluidic devices. | |
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MedLine Citation:
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PMID: 20493286 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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This review critically summarises recent novel and advanced achievements in the application of monolithic materials and related porous polymer gels in micro-fluidic devices appearing within the literature over the period of the last 5 years (2005-2010). The range of monolithic materials has developed rapidly over the past decade, with a diverse and highly versatile class of materials now available, with each exhibiting distinct porosities, pore sizes, and a wide variety of surface functionalities. A major advantage of these materials is their ease of preparation in micro-fluidic channels by in situ polymerisation, leading to monolithic materials being increasingly utilised for a larger variety of purposes in micro-fluidic platforms. Applications of porous polymer monoliths, silica-based monoliths and related homogeneous porous polymer gels in the preparation of separation columns, ion-permeable membranes, preconcentrators, extractors, electrospray emitters, micro-valves, electrokinetic pumps, micro-reactors and micro-mixers in micro-fluidic devices are discussed herein. Procedures used in the preparation of monolithic materials in micro-channels, as well as some practical aspects of the micro-fluidic chip fabrication are addressed. Recent analytical/bioanalytical and catalytic applications of the final micro-fluidic devices incorporating monolithic materials are also reviewed. |
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Authors:
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Mercedes Vázquez; Brett Paull |
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Publication Detail:
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Type: Journal Article; Research Support, Non-U.S. Gov't; Review Date: 2010-04-24 |
Journal Detail:
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Title: Analytica chimica acta Volume: 668 ISSN: 1873-4324 ISO Abbreviation: Anal. Chim. Acta Publication Date: 2010 Jun |
Date Detail:
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Created Date: 2010-05-24 Completed Date: 2010-08-18 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 0370534 Medline TA: Anal Chim Acta Country: Netherlands |
Other Details:
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Languages: eng Pagination: 100-13 Citation Subset: IM |
Copyright Information:
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Copyright 2010 Elsevier B.V. All rights reserved. |
Affiliation:
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Irish Separation Science Cluster, National Centre for Sensor Research, Dublin City University, Glasnevin, Dublin 9, Dublin, Ireland. mercedes.vazquez@dcu.ie |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Analytic Sample Preparation Methods
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instrumentation Capillary Electrochromatography / methods Catalysis Chromatography, Liquid / methods Electrochemical Techniques Microchemistry* / methods Microfluidic Analytical Techniques* / instrumentation, methods Miniaturization / methods Polymers* / chemical synthesis, chemistry Solid Phase Microextraction / methods |
| Chemical | |
Reg. No./Substance:
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0/Polymers |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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