Document Detail


Review peptides and proteins wired into the electrical circuits: An SPM-based approach.
MedLine Citation:
PMID:  23335169     Owner:  NLM     Status:  In-Data-Review    
Abstract/OtherAbstract:
Development of molecular scale electronics stimulates the search for new functional materials and compounds. One of the promising directions of further growth within this field is bioelectronics, which assumes the use of electron transfer (ET)-mediating properties of bio-related compounds. Because of the structural and functional versatility, peptides and proteins are particularly well suited to perform as single-molecule-based elements of circuits or sensing devices. In this review, it is demonstrated that purposely designed systems such as molecular junctions are excellent platforms for the studies of ET properties of peptides and proteins at nanoscale level. Using experimental approach based on scanning probe microscopy, individual molecules can be directly wired between two metallic contacts, and their conductance can be determined. ET behavior of the peptides and proteins can be analyzed in terms of their applicability as molecular wires, switches, diodes and elements of sensing devices. © 2012 Wiley Periodicals, Inc. Biopolymers (Pept Sci) 100: 71-81, 2013.
Authors:
Slawomir Sek
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Biopolymers     Volume:  100     ISSN:  0006-3525     ISO Abbreviation:  Biopolymers     Publication Date:  2013 Apr 
Date Detail:
Created Date:  2013-01-21     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0372525     Medline TA:  Biopolymers     Country:  United States    
Other Details:
Languages:  eng     Pagination:  71-81     Citation Subset:  IM    
Copyright Information:
Copyright © 2012 Wiley Periodicals, Inc.
Affiliation:
Department of Chemistry, University of Warsaw, Pasteura 1, 02-093 Warsaw, Poland. slasek@chem.uw.edu.pl.
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