Document Detail


Review of medical abortion using mifepristone in combination with a prostaglandin analogue.
MedLine Citation:
PMID:  16781264     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Induced abortion is still a major health problem in the world and the most frequently performed intervention in obstetrics and gynecology with an estimated total of 46 million worldwide each year. Medical abortion with mifepristone and prostaglandin was first introduced in 1988 and is now approved in 31 countries. This combination of drugs has recently been included in the List of Essential Medicines by the World Health Organisation. The present review summarizes the development, physiology and the development of the currently used regimens.
Authors:
Christian Fiala; Kristina Gemzel-Danielsson
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Publication Detail:
Type:  Journal Article; Review     Date:  2006-05-19
Journal Detail:
Title:  Contraception     Volume:  74     ISSN:  0010-7824     ISO Abbreviation:  Contraception     Publication Date:  2006 Jul 
Date Detail:
Created Date:  2006-06-19     Completed Date:  2006-11-22     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0234361     Medline TA:  Contraception     Country:  United States    
Other Details:
Languages:  eng     Pagination:  66-86     Citation Subset:  IM    
Affiliation:
Gynmed Clinic, Mariahilferguertel 37, A-1150 Vienna, Austria. christian.fiala@aon.at
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MeSH Terms
Descriptor/Qualifier:
Abortifacient Agents, Nonsteroidal / administration & dosage
Abortifacient Agents, Steroidal / administration & dosage*
Abortion, Induced / methods*
Administration, Intravaginal
Administration, Sublingual
Analgesia, Obstetrical
Female
Gestational Age
Humans
Mifepristone / administration & dosage*,  adverse effects,  pharmacokinetics
Misoprostol / administration & dosage,  adverse effects,  pharmacokinetics
Patient Satisfaction
Pregnancy
Prostaglandins / administration & dosage*
Time Factors
Uterine Contraction / drug effects
Uterine Hemorrhage
World Health Organization
Chemical
Reg. No./Substance:
0/Abortifacient Agents, Nonsteroidal; 0/Abortifacient Agents, Steroidal; 0/Prostaglandins; 59122-46-2/Misoprostol; 84371-65-3/Mifepristone

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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