| Review of epidemiology and clinical risk factors for severe respiratory syncytial virus (RSV) infection. | |
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MedLine Citation:
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PMID: 14615709 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Respiratory syncytial virus (RSV) infection is the most frequent reason for hospitalization of infants in developed countries. Premature birth without or, especially, with chronic lung disease of prematurity, congenital heart disease, and T-cell immunodeficiency are conditions that predispose to more severe forms of RSV infection. Incomplete development of the airway, damage to the airway, and airway hyperreactivity underlie the increased morbidity of RSV infection in prematurely born infants. Pulmonary hypertension and cyanosis are associated with worse outcomes in infants with congenital heart disease, and prolonged viral replication accounts for more severe illness in immunocompromised individuals. |
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Authors:
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Robert C Welliver |
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Publication Detail:
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Type: Journal Article; Review |
Journal Detail:
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Title: The Journal of pediatrics Volume: 143 ISSN: 0022-3476 ISO Abbreviation: J. Pediatr. Publication Date: 2003 Nov |
Date Detail:
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Created Date: 2003-11-17 Completed Date: 2004-01-13 Revised Date: 2004-11-17 |
Medline Journal Info:
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Nlm Unique ID: 0375410 Medline TA: J Pediatr Country: United States |
Other Details:
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Languages: eng Pagination: S112-7 Citation Subset: AIM; IM |
Affiliation:
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Department of Pediatrics, State University of New York at Buffalo, School of Medicine and Biomedical Sciences, and the Division of Infectious Diseases, Children's Hospital of Buffalo, New York 14222, USA. rwelliver@upa.chob.edu |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Bronchiolitis
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pathology,
virology Child, Preschool Chronic Disease Gestational Age Heart Defects, Congenital / epidemiology Humans Immunocompromised Host Infant Infant, Newborn Infant, Premature Lung Diseases / pathology, virology Respiratory Syncytial Virus Infections / epidemiology*, immunology, virology* Risk Factors Severity of Illness Index |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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