Document Detail


Review on diagnosis and treatment of focal segmental glomerulosclerosis.
MedLine Citation:
PMID:  18219061     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Focal segmental glomerulosclerosis (FSGS) is one the most important causes of the nephrotic syndrome in adult patients. FSGS is not a disease entity. The identification of underlying causes of FSGS (secondary FSGS) has increased our insight into the pathogenesis of FSGS. Moreover, differentiating between primary (idiopathic) and secondary forms of FSGS is important to allow appropriate treatment. Recently a new pathological classification of FSGS was proposed, expanding FSGS to include nonsclerotic lesions. In this review we discuss the current diagnostic and therapeutic options in patients with FSGS.
Authors:
J K J Deegens; E J Steenbergen; J F M Wetzels
Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't; Review    
Journal Detail:
Title:  The Netherlands journal of medicine     Volume:  66     ISSN:  0300-2977     ISO Abbreviation:  Neth J Med     Publication Date:  2008 Jan 
Date Detail:
Created Date:  2008-01-25     Completed Date:  2008-02-28     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0356133     Medline TA:  Neth J Med     Country:  Netherlands    
Other Details:
Languages:  eng     Pagination:  3-12     Citation Subset:  IM    
Affiliation:
Department of Nephrology, Radboud University Nijmegen Medical Centre, Nijmegen, the Netherlands. j.deegens@nier.umcn.nl
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MeSH Terms
Descriptor/Qualifier:
Angiotensin-Converting Enzyme Inhibitors / therapeutic use
Glomerulosclerosis, Focal Segmental / diagnosis*,  drug therapy,  physiopathology
Humans
Immunosuppressive Agents
Practice Guidelines as Topic
Prognosis
Chemical
Reg. No./Substance:
0/Angiotensin-Converting Enzyme Inhibitors; 0/Immunosuppressive Agents

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