Document Detail


Review article: explaining risks of inflammatory bowel disease therapy to patients.
MedLine Citation:
PMID:  21083583     Owner:  NLM     Status:  In-Process    
Abstract/OtherAbstract:
BACKGROUND: Medical treatment for inflammatory bowel disease (IBD) has advanced significantly over the past decade, but it is important to communicate effectively the balance of benefits and risks of therapy to patients to facilitate informed medical decisions.
AIM: To review the available data describing the risk of side effects of IBD medications and to describe effective methods for communicating risk.
METHODS: To identify relevant articles for this review, a PubMed search was conducted using relevant key words and phrases. In addition, reference lists from identified manuscripts were searched and recent abstracts from National meetings were reviewed.
RESULTS: The steroid-sparing medications used for the treatment of IBD all carry risks of both common and rare adverse events. Trade-offs need to be made between the risks of these medications vs. the risks of poorly treated disease and corticosteroids. There has been significant research on how best to present risk data to patients, which is summarized in this review.
CONCLUSIONS: To ensure that our patients understand their choices and feel comfortable with their treatment, we need to communicate risk data to patients clearly. Patients comprehend absolute numbers better than relative risk, and when available, pictorial representations of data are preferred over solely presenting numerical outcomes.
Authors:
C A Siegel
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Publication Detail:
Type:  Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't     Date:  2010-10-26
Journal Detail:
Title:  Alimentary pharmacology & therapeutics     Volume:  33     ISSN:  1365-2036     ISO Abbreviation:  Aliment. Pharmacol. Ther.     Publication Date:  2011 Jan 
Date Detail:
Created Date:  2010-12-06     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8707234     Medline TA:  Aliment Pharmacol Ther     Country:  England    
Other Details:
Languages:  eng     Pagination:  23-32     Citation Subset:  IM    
Copyright Information:
© 2010 Blackwell Publishing Ltd.
Affiliation:
Dartmouth-Hitchcock Medical Center, Lebanon, NH 03756, USA. corey.a.siegel@hitchcock.org
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MeSH Terms
Descriptor/Qualifier:
Grant Support
ID/Acronym/Agency:
K23DK078678/DK/NIDDK NIH HHS

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