Document Detail

Review article: the diagnosis and treatment of haematinic deficiency in gastrointestinal disease.
MedLine Citation:
PMID:  9726380     Owner:  NLM     Status:  MEDLINE    
Deficiency of any of the vitamins and minerals essential for normal erythropoiesis (haematinics), including iron, copper, cobalt, vitamins A, B12, B6, C, E, folic acid, riboflavin and nicotinic acid, may be associated with defective erythropoiesis and anaemia. Iron, vitamin B12 and folate are the haematinics for which deficiency states manifest most often clinically and are the focus of this review. The normal absorption of these haematinics and gastrointestinal causes of their deficiency are described. Investigations, including the use of homocysteine metabolite levels and new techniques such as serum transferrin receptor assays, and treatment of haematinic deficiency are discussed in detail.
R Pawson; A Mehta
Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  Alimentary pharmacology & therapeutics     Volume:  12     ISSN:  0269-2813     ISO Abbreviation:  Aliment. Pharmacol. Ther.     Publication Date:  1998 Aug 
Date Detail:
Created Date:  1998-11-06     Completed Date:  1998-11-06     Revised Date:  2005-11-16    
Medline Journal Info:
Nlm Unique ID:  8707234     Medline TA:  Aliment Pharmacol Ther     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  687-98     Citation Subset:  IM    
Department of Haematology, Royal Free Hospital School of Medicine, London, UK.
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MeSH Terms
Deficiency Diseases / diagnosis,  physiopathology*,  therapy
Diagnosis, Differential
Erythropoiesis / physiology*
Folic Acid Deficiency
Gastrointestinal Diseases / diagnosis,  physiopathology*,  therapy
Iron / deficiency
Receptors, Transferrin / analysis
Vitamin B 12 Deficiency
Reg. No./Substance:
0/Hematinics; 0/Receptors, Transferrin; 7439-89-6/Iron
Comment In:
Aliment Pharmacol Ther. 1999 Apr;13(4):567   [PMID:  10215744 ]

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