| Review article: Tissue engineering of semilunar heart valves: current status and future developments. | |
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MedLine Citation:
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PMID: 15086267 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Heart valve replacement represents the most common surgical therapy for end-stage valvular heart diseases. One major drawback that all heart valve replacements have in common is the lack of growth, repair, and remodeling capability once implanted into the body. The emerging field of tissue engineering is focusing on the in-vitro generation of functional, living semilunar heart valve replacements. This review presents a state-of-the-art overview of the physiological and biomechanical requirements of semilunar heart valves, focusing on the aortic valve. Moreover, recent heart valve tissue engineering is summarized and future options and improvements on the way towards clinical applications are discussed. |
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Authors:
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Anita Mol; Carlijn V C Bouten; Frank P T Baaijens; Gregor Zünd; Marko I Turina; Simon P Hoerstrup |
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Publication Detail:
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Type: Journal Article; Review |
Journal Detail:
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Title: The Journal of heart valve disease Volume: 13 ISSN: 0966-8519 ISO Abbreviation: J. Heart Valve Dis. Publication Date: 2004 Mar |
Date Detail:
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Created Date: 2004-04-16 Completed Date: 2004-11-06 Revised Date: 2006-05-04 |
Medline Journal Info:
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Nlm Unique ID: 9312096 Medline TA: J Heart Valve Dis Country: England |
Other Details:
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Languages: eng Pagination: 272-80 Citation Subset: IM |
Affiliation:
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University Hospital Zurich, Clinic for Cardiovascular Surgery, Zurich, Switzerland. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Animals Aortic Valve / pathology, surgery Bioprosthesis / trends Forecasting Heart Valve Diseases / surgery Heart Valve Prosthesis / trends* Heart Valve Prosthesis Implantation / trends Humans Prosthesis Design / trends Tissue Engineering / trends* |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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