Document Detail


Review series: What goes around, comes around: childhood influences on later lung health? Long-term follow-up of infants with lung disease of prematurity.
MedLine Citation:
PMID:  21084550     Owner:  NLM     Status:  In-Process    
Abstract/OtherAbstract:
The incidence of live preterm birth is increasing and concomitantly the survival of preterm babies has increased over the last 30 years due to advances in neonatal care. Bronchopulmonary dysplasia (BPD) is a chronic respiratory disease that develops as a consequence of perinatal and/or neonatal lung injury following preterm birth and the pathology has also changed with changes in neonatal care. There are data suggesting that there is increased respiratory morbidity of ex-preterm subjects in childhood. It is only now that large populations of preterm subjects are reaching adulthood and may be at risk of persistent respiratory morbidity. This review will summarize the current knowledge in adulthood of respiratory sequelae following preterm birth; specifically it will review respiratory symptoms, pulmonary function, exercise capacity and structural lung disease as determined by high resolution computed tomography scans in ex-preterm survivors with and without BPD. Whether prematurity-related lung disease is associated with chronic obstructive airways disease will be discussed.
Authors:
Indra Narang
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Chronic respiratory disease     Volume:  7     ISSN:  1479-9731     ISO Abbreviation:  Chron Respir Dis     Publication Date:  2010  
Date Detail:
Created Date:  2010-11-18     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101197408     Medline TA:  Chron Respir Dis     Country:  England    
Other Details:
Languages:  eng     Pagination:  259-69     Citation Subset:  IM    
Affiliation:
Division of Respiratory Medicine, Hospital for Sick Children, 555 University Avenue, Toronto, Ontario, Canada. indra.narang@sickkids.ca
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