Document Detail

Reproductive-endocrine point-of-care testing: current status and limitations.
MedLine Citation:
PMID:  20446758     Owner:  NLM     Status:  MEDLINE    
Point-of-care (POC) testing for the detection of pregnancy and the prediction of ovulation has grown and evolved since the introduction of the first qualitative pregnancy test marketed directly to the consumer over three decades ago. Numerous publications have analyzed both pregnancy and ovulation prediction devices for their sensitivity, accuracy and general utility. Despite vast improvements in ease-of-use and sensitivity from their earlier forms, the primary literature regarding the utility of these devices is at times incomplete. This article reviews the literature focusing on the sensitivity and accuracy of the modern urine-luteinizing hormone ovulation prediction devices, and the effect these devices have on fertility rates. In addition, the analytical sensitivity and clinical utility of POC pregnancy tests will be reviewed, along with the potential causes of false negative and false positive results.
Mark A Cervinski; Ann M Gronowski
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Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  Clinical chemistry and laboratory medicine : CCLM / FESCC     Volume:  48     ISSN:  1434-6621     ISO Abbreviation:  Clin. Chem. Lab. Med.     Publication Date:  2010 Jul 
Date Detail:
Created Date:  2010-06-29     Completed Date:  2010-11-16     Revised Date:  2013-08-23    
Medline Journal Info:
Nlm Unique ID:  9806306     Medline TA:  Clin Chem Lab Med     Country:  Germany    
Other Details:
Languages:  eng     Pagination:  935-42     Citation Subset:  IM    
Department of Pathology, Dartmouth Medical School and Dartmouth-Hitchcock Medical Center, Lebanon, NH, USA.
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MeSH Terms
Chorionic Gonadotropin / analysis
Diagnostic Errors
Luteinizing Hormone / analysis
Point-of-Care Systems*
Pregnancy Tests / methods*
Reg. No./Substance:
0/Chorionic Gonadotropin; 9002-67-9/Luteinizing Hormone
Comment In:
Clin Chem Lab Med. 2013 Jul;51(7):e149-50   [PMID:  23370909 ]

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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