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A Review of a Paediatric Emergency Department Vaccination Programme for Patients at Risk of Allergy/Anaphylaxis.
MedLine Citation:
PMID:  22612789     Owner:  NLM     Status:  Publisher    
Aim:  We sought to review the clinical outcomes of patients referred to our Emergency Department (ED) vaccination service for children with a history of allergy or anaphylaxis or in whom there was a concern of a significant adverse reaction. Methods:  This was a prospective observational cohort study set in an urban tertiary Paediatric ED. All attendances for any childhood vaccination for a 5-year period (from the 1(st) of Jan 2006 to the 31(st) of December 2010) were included. Our primary outcome measure was any adverse reaction as a result of the vaccine administered. Results:  A total of 446 vaccines were administered during the study period in 374 patients. Of these vaccinations, 310 (69.5%) were Measles, Mumps, Rubella (MMR). The majority of patients (348, 93%) were referred from the community. Suspected egg allergy was the reason for the majority of referrals for MMR (261/310 (84.2%)). Only 6 patients (1.3%) experienced an immediate reaction to a vaccination. All reactions were minor. Conclusion:  This is one of the largest studies looking at childhood vaccinations performed in a hospital setting for children who are "at-risk" of allergy, anaphylaxis or hypersensitivity. A significant number of referrals were unwarranted and the majority could have been safely managed in the community. © 2012 The Author(s)/Acta Paediatrica © 2012 Foundation Acta Paediatrica.
John Cronin; Annemarie Scorr; Sinead Russell; Siobhan McCoy; Sean Walsh; Ronan O'Sullivan
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Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2012-5-22
Journal Detail:
Title:  Acta paediatrica (Oslo, Norway : 1992)     Volume:  -     ISSN:  1651-2227     ISO Abbreviation:  -     Publication Date:  2012 May 
Date Detail:
Created Date:  2012-5-22     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9205968     Medline TA:  Acta Paediatr     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Copyright Information:
© 2012 The Author(s)/Acta Paediatrica © 2012 Foundation Acta Paediatrica.
Paediatric Emergency Research Unit (PERU), Department of Emergency Medicine, Our Lady's Children's Hospital, Crumlin, Dublin 12, Ireland The National Children's Research Centre, Our Lady's Children's Hospital, Crumlin, Dublin 12, Ireland Department of Paediatrics, University College Dublin, Ireland.
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