| Review. Non-papillary urothelial lesions of the urinary bladder: morphological classification and immunohistochemical markers. | |
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MedLine Citation:
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PMID: 18712178 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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In the past quarter century, several nomenclature systems for non-papillary urothelial lesions of the urinary bladder have been proposed. The 1998 World Health Organization and International Society of Urological Pathology (WHO/ISUP) classification recommended a four-tier system for the subdivision of flat intraepithelial lesions of the bladder. This classification was adopted by the WHO in 1999 and revised in 2004. In 2002, a more detailed classification of flat urothelial lesions was based on the Ancona International Consultation. Each of these lesions was defined with strict morphological criteria to provide more accurate information to urologists in managing patients. However, immunohistochemical markers including proliferation markers, cytoskeletal proteins, growth factors and their related receptors, cell adhesion molecules and oncogene proteins are increasingly being used in order to differentiate histologically similar lesions. |
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Authors:
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Constantina D Petraki; Constantinos P Sfikas |
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Publication Detail:
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Type: Journal Article; Review |
Journal Detail:
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Title: In vivo (Athens, Greece) Volume: 22 ISSN: 0258-851X ISO Abbreviation: In Vivo Publication Date: 2008 Jul-Aug |
Date Detail:
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Created Date: 2008-08-20 Completed Date: 2008-09-19 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 8806809 Medline TA: In Vivo Country: Greece |
Other Details:
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Languages: eng Pagination: 493-501 Citation Subset: IM |
Affiliation:
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Renal Pathology Department, Evangelismos Hospital, Athens, Greece. nelniko@otenet.gr |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Cell Adhesion Molecules
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metabolism Cell Proliferation Chromosome Mapping Cytoskeleton / metabolism Epithelium / metabolism Gene Deletion Homozygote Humans Immunohistochemistry / methods* Mucous Membrane / pathology Precancerous Conditions Prognosis Urinary Bladder / injuries*, pathology Urinary Bladder Neoplasms / diagnosis*, pathology Urothelium / pathology* |
| Chemical | |
Reg. No./Substance:
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0/Cell Adhesion Molecules |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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